Within Family Selection

Typically, the select() function of the BSL performs mass-selection: it ranks all individuals (in the most-recently created population by default) and selects the top individuals (top 40 by default). If the option type="WithinFamily" is specified, however, then select() ranks families separately and picks the top nSelect individuals per family. A “family” is defined by the first parent, i.e., all progeny of the same parent 1 are considered part of the same family.

Load the BreedingSchemeLanguage.

library(BreedingSchemeLanguage)

Avoid writing over a previously existing simulation environment

if (exists("simEnv")){
  rm(list=names(simEnv), envir=simEnv)
  rm(simEnv)
}

Use data in an appropriately formatted HapMap file

Some hapmap data comes with the package. Find it. Load the historical haplotypes into the simulation environment Initialize the founder population with 20 individuals

The vignette also illustrates the difference between “Cycle” and “Population” in the BSL. The functions cross(), selfFertilize(), and doubledHaploid() increment the Cycle and the Population, while the function select() increments only the Population. This is relevant for functions that require Population to be specified. It is also relevant for plotData() which by default shows Cycles but can be parameterized to show Populations.

filePathName <- system.file("extdata", "exampleHapMapFile.hmp", package = "BreedingSchemeLanguage")
simEnv <- defineSpecies(loadData=NULL, importFounderHap=filePathName, nMarkers=350)
initializePopulation(nInd=20) # Create Population 0, Cycle 0

Make S1 families out of the founders

The function selfFertilize creates nProgeny=100 by default. So each of the 20 founders will generate 5 selfed progeny Phenotype and select on those phenotypes, 2 individuals per family Cross at random while imposing that individuals from the same family are not crossed. By default, cross() makes 100 S0 progeny.

selfFertilize() # Create Population 1, Cycle 1
phenotype()
select(nSelect=2, type="WithinFamily") # Create Population 2, Cycle 1
cross(notWithinFam=T) # Create Population 3, Cycle 2

Select among S0 then self and perform within-family selection again

This chunk largely repeats the cycle of the previous chunk

phenotype()
select(nSelect=20) # Create Population 4, Cycle 2
selfFertilize() # Create Population 5, Cycle 3
phenotype()
select(nSelect=2, type="WithinFamily") # Create Population 6, Cycle 3
cross(notWithinFam=T) # Create Population 7, Cycle 4
plotData()

plotData(popID=list(0, 1, 2, 3, 4, 5, 6, 7))