The 2017 American College of Cardiology and American Heart
  Association blood pressure guideline recommends using 10-year predicted 
  atherosclerotic cardiovascular disease risk to guide the decision to 
  initiate or intensify antihypertensive medication. The guideline recommends 
  using the Pooled Cohort risk prediction equations to predict 10-year 
  atherosclerotic cardiovascular disease risk. This package implements the 
  original Pooled Cohort risk prediction equations and also incorporates 
  updated versions based on more contemporary data and statistical methods.

Calculates the pooled mean group (PMG) estimator for dynamic panel data models, as described by Pesaran, Shin and Smith (1999) <doi:10.1080/01621459.1999.10474156>.

Functions for the computation of f- and D-statistics (estimation of 'Fst', Patterson's 'F2', 'F3', 'F3*', 'F4' and D parameters) in population genomics studies from allele count or Pool-Seq read count data and for the fitting, building and visualization of admixture graphs. The package also includes several utilities to manipulate Pool-Seq data stored in standard format (e.g., such as 'vcf' files or 'rsync' files generated by the the 'PoPoolation' software) and perform conversion to alternative format (as used in the 'BayPass' and 'SelEstim' software). As of version 2.0, the package also includes utilities to manipulate standard allele count data (e.g., stored in 'TreeMix', 'BayPass' or 'SelEstim' format).

Simulates pooled sequencing data under a variety of conditions. 
    Also allows for the evaluation of the average absolute difference between allele frequencies 
    computed from genotypes and those computed from pooled data. 
    Carvalho et al., (2022) <doi:10.1101/2023.01.20.524733>.

Functions for calculating power and fitting regression models in studies where a biomarker is measured in "pooled" samples rather than for each individual. Approaches for handling measurement error follow the framework of Schisterman et al. (2010) <doi:10.1002/sim.3823>.