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BBNI: Bayesian Inference of Boolean Genetic Networks

Implements a fully Bayesian Markov chain Monte Carlo (MCMC) approach for inferring the topology and Boolean logic transition functions of gene regulatory networks from noisy, binary time-series expression data. Network structure and Boolean rules are sampled jointly from their posterior distribution, providing principled uncertainty quantification rather than a single point estimate. Method described in Han et al. (2014) <doi:10.1371/journal.pone.0115806>.

Version: 0.1.1
Depends: R (≥ 4.1.0)
Imports: bitops, stats
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2026-07-15
DOI: 10.32614/CRAN.package.BBNI (may not be active yet)
Author: Anson Li [aut, cre], Shengtong Han [aut]
Maintainer: Anson Li <liyuanrui618 at gmail.com>
BugReports: https://github.com/anson-li8/BBNI/issues
License: BSD_3_clause + file LICENSE
URL: https://anson-li8.github.io/BBNI/, https://github.com/anson-li8/BBNI
NeedsCompilation: no
Language: en-US
Citation: BBNI citation info
Materials: README, NEWS
CRAN checks: BBNI results

Documentation:

Reference manual: BBNI.html , BBNI.pdf
Vignettes: Bayesian Boolean Network Inference with BBNI (source)

Downloads:

Package source: BBNI_0.1.1.tar.gz
Windows binaries: r-devel: not available, r-release: BBNI_0.1.1.zip, r-oldrel: not available
macOS binaries: r-release (arm64): BBNI_0.1.1.tgz, r-oldrel (arm64): BBNI_0.1.1.tgz, r-release (x86_64): BBNI_0.1.1.tgz, r-oldrel (x86_64): BBNI_0.1.1.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=BBNI to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.