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IsletCalc: Calculators for Insulin and Glucagon Release Indices

Facilitates the calculation of validated pancreatic islet hormone-release indices from fasting and oral glucose tolerance test (OGTT) measurements. Provides beta-cell insulin release indices (including HOMA-beta, corrected insulin response, Stumvoll first-phase index, BIGTT-AIR, and disposition indices) as described in Madsen (2024) <doi:10.1038/s42255-024-01140-6>, alongside alpha-cell glucagon release and glucagon resistance indices derived from the glucagon-suppression and liver-alpha-cell-axis literature. Enables reproducible assessment of beta-cell and alpha-cell function for metabolic and endocrine research.

Version: 0.0.1
Depends: R (≥ 3.5.0)
Suggests: knitr, rmarkdown, spelling, testthat (≥ 3.0.0)
Published: 2026-07-16
DOI: 10.32614/CRAN.package.IsletCalc (may not be active yet)
Author: Sufyan Suleman ORCID iD [aut, cre]
Maintainer: Sufyan Suleman <sufyansuleman at hotmail.com>
BugReports: https://github.com/sufyansuleman/IsletCalc/issues
License: MIT + file LICENSE
URL: https://github.com/sufyansuleman/IsletCalc, https://sufyansuleman.github.io/IsletCalc/
NeedsCompilation: no
Language: en-US
Citation: IsletCalc citation info
Materials: README, NEWS
CRAN checks: IsletCalc results

Documentation:

Reference manual: IsletCalc.html , IsletCalc.pdf
Vignettes: Get started with IsletCalc (source, R code)

Downloads:

Package source: IsletCalc_0.0.1.tar.gz
Windows binaries: r-devel: IsletCalc_0.0.1.zip, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): IsletCalc_0.0.1.tgz, r-oldrel (arm64): IsletCalc_0.0.1.tgz, r-release (x86_64): IsletCalc_0.0.1.tgz, r-oldrel (x86_64): IsletCalc_0.0.1.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=IsletCalc to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.