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This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' <http://quodata.de/>. The modelling itself has been described by Uhlig et al. (2015) <doi:10.1007/s00769-015-1112-9>.
| Version: | 1.2.0 |
| Depends: | R (≥ 3.4.0) |
| Published: | 2020-06-30 |
| Author: | Markus Boenn (State Office for Consumer Protection Saxony-Anhalt, Germany) |
| Maintainer: | Markus Boenn <markus.boenn.sf at gmail.com> |
| License: | GPL-3 |
| NeedsCompilation: | no |
| Citation: | POD citation info |
| Materials: | README NEWS ChangeLog |
| In views: | Omics |
| CRAN checks: | POD results |
| Reference manual: | POD.pdf |
| Vignettes: |
excelmacro |
| Package source: | POD_1.2.0.tar.gz |
| Windows binaries: | r-devel: POD_1.2.0.zip, r-release: POD_1.2.0.zip, r-oldrel: POD_1.2.0.zip |
| macOS binaries: | r-release (arm64): POD_1.2.0.tgz, r-oldrel (arm64): POD_1.2.0.tgz, r-release (x86_64): POD_1.2.0.tgz, r-oldrel (x86_64): POD_1.2.0.tgz |
| Old sources: | POD archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.