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TaxNorm is the R package for a novel feature-wise normalization method for microbiome data based on zero-inflated negative binomial model. This method assumes that the effects of sequencing depth vary for each taxon on their mean and incorporates a rational link of zero probability and taxon dispersion as a function of sequencing depth to better capture the microbiome data nature.
Current stable release:
Build from GitHub:
if (!require(remotes)) install.packages("remotes")
remotes::install_github("wangziyue57/TaxaNorm",
dependencies = TRUE,
build_vignettes = TRUE)These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.