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mhtopt: Optimal Multiple Hypothesis Testing Corrections

Implements the optimal multiple hypothesis testing correction from Viviano, Wuthrich, and Niehaus (2026) <doi:10.48550/arXiv.2104.13367>. Derives the optimal per-test significance level from the economic incentives of research production, providing a correction that lies between Bonferroni (too conservative) and unadjusted (too permissive). Supports two cost models: a Linear one calibrated to United States Food and Drug Administration (FDA) clinical-trial costs, and a Cobb-Douglas one calibrated to Abdul Latif Jameel Poverty Action Lab (J-PAL) project costs. Reports optimal, Bonferroni, Holm, Benjamini-Hochberg (BH), and unadjusted results side by side.

Version: 1.0.0
Imports: stats
Suggests: testthat (≥ 3.0.0), haven, fixest, estimatr, knitr, rmarkdown
Published: 2026-07-29
DOI: 10.32614/CRAN.package.mhtopt
Author: Davide Viviano [aut], Kaspar Wuthrich [aut], Paul Niehaus [aut], Erick Rosas Lopez [cre, ctb]
Maintainer: Erick Rosas Lopez <erosaslpez at ucsd.edu>
BugReports: https://github.com/dviviano/mhtopt/issues
License: MIT + file LICENSE
URL: https://github.com/dviviano/mhtopt
NeedsCompilation: no
Language: en-US
Citation: mhtopt citation info
Materials: README, NEWS
CRAN checks: mhtopt results

Documentation:

Reference manual: mhtopt.html , mhtopt.pdf
Vignettes: Optimal Multiple Hypothesis Testing (source, R code)

Downloads:

Package source: mhtopt_1.0.0.tar.gz
Windows binaries: r-devel: mhtopt_1.0.0.zip, r-release: mhtopt_1.0.0.zip, r-oldrel: mhtopt_1.0.0.zip
macOS binaries: r-release (arm64): mhtopt_1.0.0.tgz, r-oldrel (arm64): mhtopt_1.0.0.tgz, r-release (x86_64): mhtopt_1.0.0.tgz, r-oldrel (x86_64): mhtopt_1.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=mhtopt to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.