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rxode2lincmt: Linear Compartment Model Solutions and Gradients for 'rxode2'
Analytic one, two and three compartment linear pharmacokinetic
solutions with their parameter gradients from 'stan' automatic
differentiation (Carpenter et al (2015) <doi:10.48550/arXiv.1509.07164>),
eigen decompositions and derived-parameter conversions used by 'rxode2'
(Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>). Split out of
'rxode2' so its installation does not compile 'stan' AD items which made it
take too long to compile by itself.
The closed-form solutions follow the idea of the 'wnl' package
(Bae, <https://CRAN.R-project.org/package=wnl>), though the
implementation here is different.
| Version: |
0.1.0 |
| Depends: |
R (≥ 4.1.0) |
| Imports: |
Rcpp (≥ 1.0.8), checkmate |
| LinkingTo: |
Rcpp (≥ 1.0.8), RcppEigen (≥ 0.3.3.9.2), StanHeaders (≥
2.21.0.7), BH, RcppParallel |
| Suggests: |
covr, testthat (≥ 3.0.0) |
| Published: |
2026-09-24 |
| DOI: |
10.32614/CRAN.package.rxode2lincmt (may not be active yet) |
| Author: |
Matthew L. Fidler 
[aut, cre],
Richard Upton [ctb] |
| Maintainer: |
Matthew L. Fidler <matthew.fidler at gmail.com> |
| BugReports: |
https://github.com/nlmixr2/rxode2lincmt/issues/ |
| License: |
GPL (≥ 3) |
| URL: |
https://nlmixr2.github.io/rxode2lincmt/,
https://github.com/nlmixr2/rxode2lincmt/ |
| NeedsCompilation: |
yes |
| Language: |
en-US |
| Materials: |
README, NEWS |
| CRAN checks: |
rxode2lincmt results |
Documentation:
Downloads:
Linking:
Please use the canonical form
https://CRAN.R-project.org/package=rxode2lincmt
to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.