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scaRabee: Optimization Toolkit for Pharmacokinetic-Pharmacodynamic Models

A port of the Scarabee toolkit originally written as a Matlab-based application. scaRabee provides a framework for simulation and optimization of pharmacokinetic-pharmacodynamic models at the individual and population level. It is built on top of the neldermead package, which provides the direct search algorithm proposed by Nelder and Mead for model optimization.

Version: 1.1-4
Depends: neldermead (≥ 1.0-8), optimsimplex (≥ 1.0-5), optimbase (≥ 1.0-8)
Imports: lattice, grid, deSolve, utils
Suggests: knitr (≥ 1.28), rmarkdown (≥ 2.2)
Published: 2022-02-04
DOI: 10.32614/CRAN.package.scaRabee
Author: Sebastien Bihorel [aut, cre]
Maintainer: Sebastien Bihorel <sb.pmlab at gmail.com>
License: GPL-3
NeedsCompilation: no
Materials: README ChangeLog
In views: Pharmacokinetics
CRAN checks: scaRabee results

Documentation:

Reference manual: scaRabee.pdf
Vignettes: manual

Downloads:

Package source: scaRabee_1.1-4.tar.gz
Windows binaries: r-devel: scaRabee_1.1-4.zip, r-release: scaRabee_1.1-4.zip, r-oldrel: scaRabee_1.1-4.zip
macOS binaries: r-release (arm64): scaRabee_1.1-4.tgz, r-oldrel (arm64): scaRabee_1.1-4.tgz, r-release (x86_64): scaRabee_1.1-4.tgz, r-oldrel (x86_64): scaRabee_1.1-4.tgz
Old sources: scaRabee archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.