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tsdf

What is it?

tsdf calculates optimal Zhong’s two-/three-stage Phase II designs, generates decision tables for two-/three-stage Phase I dose-finding, and allows users to run dose-finding simulations with custom decision tables. ### Installation To install from CRAN:

install.packages("tsdf")

References

[1] Bob Zhong, Single-arm phase IIA clinical trials with go/no-go decisions, Contemp Clin Trials, 2012

[2] Wenchuan Guo and Bob Zhong, Target toxicity design for phase I dose-finding, Statistical Theory and Related Fields, 2021

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.