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ubiquity: PKPD, PBPK, and Systems Pharmacology Modeling Tools

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.

Version: 2.0.3
Depends: R (≥ 3.5.0)
Imports: cli, deSolve, dplyr (≥ 1.0.0), digest, doParallel, flextable, foreach, ggplot2, knitr, magrittr, MASS, onbrand (≥ 1.0.2), optimx, PKNCA, pso, readxl, rmarkdown, rhandsontable, scales, stats, stringr, shiny
Suggests: GA, GGally, gridGraphics, gridExtra, grid, officer, webshot, ggrepel, rstudioapi, testthat
Published: 2024-03-08
DOI: 10.32614/CRAN.package.ubiquity
Author: John Harrold ORCID iD [aut, cre]
Maintainer: John Harrold <john.m.harrold at gmail.com>
BugReports: https://github.com/john-harrold/ubiquity/issues
License: BSD_2_clause + file LICENSE
URL: https://ubiquity.tools/rworkflow
NeedsCompilation: no
SystemRequirements: Perl
Citation: ubiquity citation info
Materials: README NEWS
In views: Pharmacokinetics
CRAN checks: ubiquity results

Documentation:

Reference manual: ubiquity.pdf
Vignettes: Deployment
Estimation
Language
Report Generation
Simulation
Titration/Rule-Based Simulations

Downloads:

Package source: ubiquity_2.0.3.tar.gz
Windows binaries: r-devel: ubiquity_2.0.3.zip, r-release: ubiquity_2.0.3.zip, r-oldrel: ubiquity_2.0.3.zip
macOS binaries: r-release (arm64): ubiquity_2.0.3.tgz, r-oldrel (arm64): ubiquity_2.0.3.tgz, r-release (x86_64): ubiquity_2.0.3.tgz, r-oldrel (x86_64): ubiquity_2.0.3.tgz
Old sources: ubiquity archive

Reverse dependencies:

Reverse suggests: ruminate

Linking:

Please use the canonical form https://CRAN.R-project.org/package=ubiquity to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.