Centered Isotonic Regression and Dose-Response Utilities

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Documentation for package ‘cir’ version 2.5.0

• DESCRIPTION file.
• User guides, package vignettes and other documentation.

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cir-package	Isotonic Regression, Centered Isotonic Regression, and Dose-Response Utilities
agcouCI	Standard unordered-Binomial confidence interval utilities.
cir	Isotonic Regression, Centered Isotonic Regression, and Dose-Response Utilities
cirPAVA	Centered-isotonic-regression (CIR) point estimation
deltaInverse	Backend utility to calculate inverse (dose-finding) intervals, using local inversion and the Delta method
doseFind	Inverse (dose-finding) point estimate (e.g., estimating a percentile)
doseResponse	Constructor functions and class-checking functions for DRtrace and doseResponse classes
DRshrink	Shrinkage fix to mitigate bias in observed rates, under adaptive dose-finding designs
DRtrace	Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.doseResponse	Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.DRtrace	Constructor functions and class-checking functions for DRtrace and doseResponse classes
isotInterval	Backend utility to calculate analytical CIR/IR interval estimates, given the point estimates
jeffCI	Standard unordered-Binomial confidence interval utilities.
morrisCI	Analytical ordered-binary-Y confidence intervals, using the Morris (1988) algorithm
oldPAVA	"Old School" isotonic-regression point estimates, with flexible dose-response input
plot.doseResponse	Plotting Methods for DRtrace, doseResponse Objects
plot.DRtrace	Plotting Methods for DRtrace, doseResponse Objects
quickInverse	Convenient point and Interval Inverse Estimation ("Dose-Finding"), using CIR or IR
quickIsotone	Convenient Forward point and interval estimation via CIR or IR
slope	Piecewise-linear local slopes given a (non-strictly) monotone x-y sequence
wilsonCI	Standard unordered-Binomial confidence interval utilities.