Group Sequential Design with Non-Constant Effect

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Documentation for package ‘gsDesign2’ version 1.0.9

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

ahr	Average hazard ratio under non-proportional hazards (test version)
as_gt	Convert summary table of a fixed or group sequential design object to a gt object
as_gt.fixed_design	Convert summary table of a fixed or group sequential design object to a gt object
as_gt.gs_design	Convert summary table of a fixed or group sequential design object to a gt object
expected_accrual	Piecewise constant expected accrual
expected_event	Expected events observed under piecewise exponential model
expected_time	Predict time at which a targeted event count is achieved
fixed_design	Fixed design sample size
gridpts	Grid points for group sequential design numerical integration
gs_b	Default boundary generation
gs_create_arm	Create npsurvSS arm object
gs_design_ahr	Group sequential design using average hazard ratio under non-proportional hazards
gs_design_combo	Group sequential design using MaxCombo test under non-proportional hazards
gs_design_npe	Group sequential design computation with non-constant effect and information
gs_design_rd	Group sequential design of binary outcome measuring in risk difference
gs_design_wlr	Group sequential design using weighted log-rank test under non-proportional hazards
gs_info_ahr	Information and effect size based on AHR approximation
gs_info_combo	Information and effect size for MaxCombo test
gs_info_rd	Information and effect size under risk difference
gs_info_wlr	Information and effect size for weighted log-rank test
gs_power_ahr	Group sequential design power using average hazard ratio under non-proportional hazards
gs_power_combo	Group sequential design power using MaxCombo test under non-proportional hazards
gs_power_npe	Group sequential bound computation with non-constant effect
gs_power_rd	Group sequential design power of binary outcome measuring in risk difference
gs_power_wlr	Group sequential design power using weighted log rank test under non-proportional hazards
gs_spending_bound	Derive spending bound for group sequential boundary
gs_spending_combo	Derive spending bound for MaxCombo group sequential boundary
h1	Initialize numerical integration for group sequential design
hupdate	Update numerical integration for group sequential design
ppwe	Piecewise exponential cumulative distribution function
s2pwe	Approximate survival distribution with piecewise exponential distribution
summary.fixed_design	Summary for fixed design or group sequential design objects
summary.gs_design	Summary for fixed design or group sequential design objects
to_integer	Rounds sample size to an even number for equal design
to_integer.fixed_design	Rounds sample size to an even number for equal design
to_integer.gs_design	Rounds sample size to an even number for equal design
wlr_weight	Weight functions for weighted log-rank test
wlr_weight_1	Weight functions for weighted log-rank test
wlr_weight_fh	Weight functions for weighted log-rank test
wlr_weight_mb	Weight functions for weighted log-rank test
wlr_weight_n	Weight functions for weighted log-rank test