Design and Analysis of Hierarchical Composite Endpoints


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Documentation for package ‘hce’ version 0.5.0

Help Pages

calcWINS A generic function for calculating win statistics
calcWINS.data.frame Win statistics calculation using a data frame
calcWINS.formula Win statistics calculation using formula syntax
calcWINS.hce Win statistics calculation for 'hce' objects
calcWO A generic function for calculating win odds
calcWO.data.frame Win odds calculation using a data frame
calcWO.formula Win odds calculation using formula syntax
calcWO.hce Win odds calculation for 'hce' objects
COVID19 COVID-19 ordinal scale dataset (full report).
COVID19b COVID-19 ordinal scale dataset (preliminary report).
hce Helper function for 'hce' objects
HCE1 'HCE1', 'HCE2', 'HCE3', 'HCE4' datasets for 1000 patients with different treatment effects.
HCE2 'HCE1', 'HCE2', 'HCE3', 'HCE4' datasets for 1000 patients with different treatment effects.
HCE3 'HCE1', 'HCE2', 'HCE3', 'HCE4' datasets for 1000 patients with different treatment effects.
HCE4 'HCE1', 'HCE2', 'HCE3', 'HCE4' datasets for 1000 patients with different treatment effects.
minWO Minimum detectable or WO for alternative hypothesis for given power (no ties)
new_hce Constructor function for 'hce' objects
plot.hce_results A print method for 'hce_results ' objects
powerWO Power calculation for the win odds test (no ties)
print.hce_results A print method for 'hce_results' objects
propWINS Proportion of wins/losses/ties given the win odds and the win ratio
regWO A generic function for win odds regression
regWO.data.frame Win odds regression using a data frame
simHCE Simulate 'hce' object with given event rates of time-to-event outcomes, mean and SD of the continuous outcome by treatment group
sizeWO Sample size calculation for the win odds test (no ties)
sizeWR Sample size calculation for the win ratio test (with WR = 1 null hypothesis)
summaryWO A generic function for summarizing win odds
summaryWO.data.frame Win odds summary for a data frame
summaryWO.formula Win odds summary using formula syntax
summaryWO.hce Win odds summary for 'hce' objects
validate_hce Validator function for 'hce' objects