Package: DrugSim2DR
Type: Package
Title: Predict Drug Functional Similarity to Drug Repurposing
Version: 0.1.1
Maintainer: Junwei Han <hanjunwei1981@163.com>
Authors@R: c(person(given = "Junwei", family = "Han", email = "hanjunwei1981@163.com", role  = c("aut", "cre", "cph")),
             person(given = "Ji", family = "Li", role  = "aut"),
             person(given = "Jiashuo", family = "Wu", role  = "aut"))
Description: A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity  in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.1
Imports: igraph, stats, pheatmap, ChemmineR, rvest, base, sp, tidyr,
        reshape2, fastmatch
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
Depends: R (>= 3.6)
NeedsCompilation: no
Packaged: 2023-08-10 03:24:09 UTC; Administrator
Author: Junwei Han [aut, cre, cph],
  Ji Li [aut],
  Jiashuo Wu [aut]
Repository: CRAN
Date/Publication: 2023-08-10 04:50:02 UTC
Built: R 4.6.0; ; 2025-10-14 03:02:52 UTC; windows
