Single-Cell Correlation Based Cell Type Annotation


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Documentation for package ‘sccca’ version 0.1.0

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calculate_cor_mat Performs aggregation based on cell clusters and condition. Then, it calculates correlation matrix of genes
calculate_normalized_ratio Calculate cell scores based on number of genes
enrich_genes Performs parallel function on two lists
filter_correlation Filter the genes based on specific correlation threshold
filter_list Process the cell markers that overlap between the cell markers and scRNA matrix
fisher_test Performs fisher exact test to get the significant overlap between genes for cell type assignment
match_characters Process the cell markers that pass specific threshold in the gene correlation matrix
phyper_test Performs phyper test to get the significant overlap between genes for cell type assignment
process_clus Gets the associated cell types using correlation-based approach
process_markers Process the cell markers database and return the processed list
sccca Run the pipeline for the cell type assignment