CRAN Package Check Results for Package ukbflow

Last updated on 2026-04-07 18:00:12 CEST.

Flavor Version Tinstall Tcheck Ttotal Status Flags
r-devel-linux-x86_64-fedora-clang 0.3.3 25.00 290.92 315.92 ERROR
r-devel-linux-x86_64-fedora-gcc 0.3.3 25.00 377.80 402.80 ERROR

Check Details

Version: 0.3.3
Check: tests
Result: ERROR Running ‘testthat.R’ [2m/90m] Running the tests in ‘tests/testthat.R’ failed. Complete output: > # This file is part of the standard setup for testthat. > # It is recommended that you do not modify it. > # > # Where should you do additional test configuration? > # Learn more about the roles of various files in: > # * https://r-pkgs.org/testing-design.html#sec-tests-files-overview > # * https://testthat.r-lib.org/articles/special-files.html > > library(testthat) > library(ukbflow) > > test_check("ukbflow") v Logged in to DNAnexus as: "TestUser" v Logged out from DNAnexus. v Project selected: "project-XXXXXXXXXXXX" v Renamed 1 column. * date_of_attending_assessment_centre_i0 v derive_hes (t2d): 26 cases, 26 with date. v derive_icd10 (t2d): 26 cases across 1 source, 26 with date. v derive_age: 1 event processed. Read '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82c2a661ef8.csv': 3 rows, 2 columns. Read '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82c7a9b7888.csv': 5 rows, 3 columns. Read '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82c125a8618.csv': 5 rows, 3 columns. v No NA values. Read '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82c30c45d2c.csv': 3 rows, 3 columns. v No NA values. v No duplicate SNPs. v All SNP IDs match rs[0-9]+ format. v All effect alleles are A/T/C/G. Read '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82c6047b891.csv': 5 rows, 3 columns. v No NA values. v No duplicate SNPs. v All effect alleles are A/T/C/G. Beta summary: Range : -0.2 to 0.3 Mean |beta|: 0.16 Positive : 3 (60%) Negative : 2 (40%) Zero : 0 v Weights file passed checks: 5 SNPs ready for UKB RAP. v Saved: '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82cd8fe08c.txt' Read '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82c4fe8c8f6.csv': 5 rows, 3 columns. v No NA values. v No duplicate SNPs. v All SNP IDs match rs[0-9]+ format. Beta summary: Range : -0.2 to 0.3 Mean |beta|: 0.16 Positive : 3 (60%) Negative : 2 (40%) Zero : 0 v Weights file passed checks: 5 SNPs ready for UKB RAP. v Saved: '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82c7bff6220.txt' Read '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82cb9cf34b.csv': 5 rows, 3 columns. v No NA values. v No duplicate SNPs. v All SNP IDs match rs[0-9]+ format. v All effect alleles are A/T/C/G. Beta summary: Range : -0.2 to 0.3 Mean |beta|: 0.16 Positive : 3 (60%) Negative : 2 (40%) Zero : 0 v Weights file passed checks: 5 SNPs ready for UKB RAP. v Saved: '/tmp/RtmpGDZMfx/working_dir/RtmpkEDi7D/file37d82cac5d83c.txt' Auto-detected 1 GRS column(s): "GRS_flat" v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_b_z -> GRS_b_z_z [mean=-0.0275, sd=0.9886] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] Auto-detected 2 GRS column(s): "GRS_a_z" and "GRS_b_z" -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_quad ---------------------------------------------------- GRS_b_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_tri ----------------------------------------------------- GRS_b_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 -- GRS_b_z -- v Unadjusted | GRS_b_z: OR 0.86 (0.63-1.17), p = 0.328 v Done: 2 result rows across 2 exposures and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 -- GRS_b_z_tri -- v Unadjusted | GRS_b_z_triMid: OR 0.51 (0.25-1.04), p = 0.063 v Unadjusted | GRS_b_z_triHigh: OR 0.67 (0.28-1.62), p = 0.377 v Done: 4 result rows across 2 exposures and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposures GRS_a_z_quad and GRS_b_z_quad are not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 2 exposures x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 -- GRS_b_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_b_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_b_z_quadQ2: OR 0.49 (0.21-1.14), p = 0.0976 v Unadjusted | GRS_b_z_quadQ3: OR 0.66 (0.30-1.48), p = 0.315 v Unadjusted | GRS_b_z_quadQ4: OR 0.54 (0.24-1.25), p = 0.151 i Unadjusted | trend: OR_per_score = 0.84 (0.65-1.11), p_trend = 0.221 v Done: 8 result rows across 2 exposures and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_quad ---------------------------------------------------- GRS_b_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_tri ----------------------------------------------------- GRS_b_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 -- GRS_b_z -- v Unadjusted | GRS_b_z: OR 0.86 (0.63-1.17), p = 0.328 v Done: 2 result rows across 2 exposures and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 -- GRS_b_z_tri -- v Unadjusted | GRS_b_z_triMid: OR 0.51 (0.25-1.04), p = 0.063 v Unadjusted | GRS_b_z_triHigh: OR 0.67 (0.28-1.62), p = 0.377 v Done: 4 result rows across 2 exposures and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposures GRS_a_z_quad and GRS_b_z_quad are not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 2 exposures x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 -- GRS_b_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_b_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_b_z_quadQ2: OR 0.49 (0.21-1.14), p = 0.0976 v Unadjusted | GRS_b_z_quadQ3: OR 0.66 (0.30-1.48), p = 0.315 v Unadjusted | GRS_b_z_quadQ4: OR 0.54 (0.24-1.25), p = 0.151 i Unadjusted | trend: OR_per_score = 0.84 (0.65-1.11), p_trend = 0.221 v Done: 8 result rows across 2 exposures and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 v Done: 1 result row across 1 exposure and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 v Done: 2 result rows across 1 exposure and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposure GRS_a_z_quad is not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 1 exposure x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 v Done: 4 result rows across 1 exposure and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (HR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_coxph ----------------------------------------------------------------- i 1 exposure x 1 model = 1 Cox regression i Input cohort: 300 participants (n/n_events/person_years reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: HR 1.12 (0.83-1.51), p = 0.465 v Done: 1 result row across 1 exposure and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_coxph ----------------------------------------------------------------- i 1 exposure x 1 model = 1 Cox regression i Input cohort: 300 participants (n/n_events/person_years reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: HR 0.82 (0.40-1.68), p = 0.585 v Unadjusted | GRS_a_z_triHigh: HR 1.19 (0.51-2.76), p = 0.685 v Done: 2 result rows across 1 exposure and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposure GRS_a_z_quad is not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 1 exposure x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: HR 0.64 (0.28-1.47), p = 0.294 v Unadjusted | GRS_a_z_quadQ3: HR 1.10 (0.52-2.31), p = 0.805 v Unadjusted | GRS_a_z_quadQ4: HR 1.05 (0.47-2.34), p = 0.905 i Unadjusted | trend: HR_per_score = 1.08 (0.83-1.41), p_trend = 0.546 v Done: 4 result rows across 1 exposure and 1 model. -- C-index --------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 v Done: 1 result row across 1 exposure and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 v Done: 2 result rows across 1 exposure and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposure GRS_a_z_quad is not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 1 exposure x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 v Done: 4 result rows across 1 exposure and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. Execution halted Flavor: r-devel-linux-x86_64-fedora-clang

Version: 0.3.3
Check: tests
Result: ERROR Running ‘testthat.R’ [2m/90m] Running the tests in ‘tests/testthat.R’ failed. Complete output: > # This file is part of the standard setup for testthat. > # It is recommended that you do not modify it. > # > # Where should you do additional test configuration? > # Learn more about the roles of various files in: > # * https://r-pkgs.org/testing-design.html#sec-tests-files-overview > # * https://testthat.r-lib.org/articles/special-files.html > > library(testthat) > library(ukbflow) > > test_check("ukbflow") v Logged in to DNAnexus as: "TestUser" v Logged out from DNAnexus. v Project selected: "project-XXXXXXXXXXXX" v Renamed 1 column. * date_of_attending_assessment_centre_i0 v derive_hes (t2d): 26 cases, 26 with date. v derive_icd10 (t2d): 26 cases across 1 source, 26 with date. v derive_age: 1 event processed. Read '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d6979e1d479.csv': 3 rows, 2 columns. Read '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d697361bf8c.csv': 5 rows, 3 columns. Read '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d691e5b8c3f.csv': 5 rows, 3 columns. v No NA values. Read '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d695a77c161.csv': 3 rows, 3 columns. v No NA values. v No duplicate SNPs. v All SNP IDs match rs[0-9]+ format. v All effect alleles are A/T/C/G. Read '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d695fda206f.csv': 5 rows, 3 columns. v No NA values. v No duplicate SNPs. v All effect alleles are A/T/C/G. Beta summary: Range : -0.2 to 0.3 Mean |beta|: 0.16 Positive : 3 (60%) Negative : 2 (40%) Zero : 0 v Weights file passed checks: 5 SNPs ready for UKB RAP. v Saved: '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d6959ec7185.txt' Read '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d692e6d73c3.csv': 5 rows, 3 columns. v No NA values. v No duplicate SNPs. v All SNP IDs match rs[0-9]+ format. Beta summary: Range : -0.2 to 0.3 Mean |beta|: 0.16 Positive : 3 (60%) Negative : 2 (40%) Zero : 0 v Weights file passed checks: 5 SNPs ready for UKB RAP. v Saved: '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d69704df9bc.txt' Read '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d6912c6e969.csv': 5 rows, 3 columns. v No NA values. v No duplicate SNPs. v All SNP IDs match rs[0-9]+ format. v All effect alleles are A/T/C/G. Beta summary: Range : -0.2 to 0.3 Mean |beta|: 0.16 Positive : 3 (60%) Negative : 2 (40%) Zero : 0 v Weights file passed checks: 5 SNPs ready for UKB RAP. v Saved: '/tmp/RtmpbYlGeJ/working_dir/RtmpKB6VlO/file27d697b2e6147.txt' Auto-detected 1 GRS column(s): "GRS_flat" v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_b_z -> GRS_b_z_z [mean=-0.0275, sd=0.9886] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] v GRS_a_z -> GRS_a_z_z [mean=-0.0218, sd=0.9873] Auto-detected 2 GRS column(s): "GRS_a_z" and "GRS_b_z" -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_quad ---------------------------------------------------- GRS_b_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_tri ----------------------------------------------------- GRS_b_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 -- GRS_b_z -- v Unadjusted | GRS_b_z: OR 0.86 (0.63-1.17), p = 0.328 v Done: 2 result rows across 2 exposures and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 -- GRS_b_z_tri -- v Unadjusted | GRS_b_z_triMid: OR 0.51 (0.25-1.04), p = 0.063 v Unadjusted | GRS_b_z_triHigh: OR 0.67 (0.28-1.62), p = 0.377 v Done: 4 result rows across 2 exposures and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposures GRS_a_z_quad and GRS_b_z_quad are not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 2 exposures x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 -- GRS_b_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_b_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_b_z_quadQ2: OR 0.49 (0.21-1.14), p = 0.0976 v Unadjusted | GRS_b_z_quadQ3: OR 0.66 (0.30-1.48), p = 0.315 v Unadjusted | GRS_b_z_quadQ4: OR 0.54 (0.24-1.25), p = 0.151 i Unadjusted | trend: OR_per_score = 0.84 (0.65-1.11), p_trend = 0.221 v Done: 8 result rows across 2 exposures and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_quad ---------------------------------------------------- GRS_b_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_b_z ------------------------------------------------------------- GRS_b_z: mean=-0.03, median=-0.06, sd=0.99, Q1=-0.64, Q3=0.67, NA=0% (n=0) -- New column: GRS_b_z_tri ----------------------------------------------------- GRS_b_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 -- GRS_b_z -- v Unadjusted | GRS_b_z: OR 0.86 (0.63-1.17), p = 0.328 v Done: 2 result rows across 2 exposures and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 2 exposures x 1 model = 2 logistic regressions i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 -- GRS_b_z_tri -- v Unadjusted | GRS_b_z_triMid: OR 0.51 (0.25-1.04), p = 0.063 v Unadjusted | GRS_b_z_triHigh: OR 0.67 (0.28-1.62), p = 0.377 v Done: 4 result rows across 2 exposures and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposures GRS_a_z_quad and GRS_b_z_quad are not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 2 exposures x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 -- GRS_b_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_b_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_b_z_quadQ2: OR 0.49 (0.21-1.14), p = 0.0976 v Unadjusted | GRS_b_z_quadQ3: OR 0.66 (0.30-1.48), p = 0.315 v Unadjusted | GRS_b_z_quadQ4: OR 0.54 (0.24-1.25), p = 0.151 i Unadjusted | trend: OR_per_score = 0.84 (0.65-1.11), p_trend = 0.221 v Done: 8 result rows across 2 exposures and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 v Done: 1 result row across 1 exposure and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 v Done: 2 result rows across 1 exposure and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposure GRS_a_z_quad is not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 1 exposure x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 v Done: 4 result rows across 1 exposure and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (HR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_coxph ----------------------------------------------------------------- i 1 exposure x 1 model = 1 Cox regression i Input cohort: 300 participants (n/n_events/person_years reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: HR 1.12 (0.83-1.51), p = 0.465 v Done: 1 result row across 1 exposure and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_coxph ----------------------------------------------------------------- i 1 exposure x 1 model = 1 Cox regression i Input cohort: 300 participants (n/n_events/person_years reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: HR 0.82 (0.40-1.68), p = 0.585 v Unadjusted | GRS_a_z_triHigh: HR 1.19 (0.51-2.76), p = 0.685 v Done: 2 result rows across 1 exposure and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposure GRS_a_z_quad is not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 1 exposure x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: HR 0.64 (0.28-1.47), p = 0.294 v Unadjusted | GRS_a_z_quadQ3: HR 1.10 (0.52-2.31), p = 0.805 v Unadjusted | GRS_a_z_quadQ4: HR 1.05 (0.47-2.34), p = 0.905 i Unadjusted | trend: HR_per_score = 1.08 (0.83-1.41), p_trend = 0.546 v Done: 4 result rows across 1 exposure and 1 model. -- C-index --------------------------------------------------------------------- v Validation complete. -- Creating GRS groups --------------------------------------------------------- -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_quad ---------------------------------------------------- GRS_a_z_quad [4 levels] Q1: n=75 (25%) Q2: n=75 (25%) Q3: n=75 (25%) Q4: n=75 (25%) <NA>: n=0 (0%) -- Source: GRS_a_z ------------------------------------------------------------- GRS_a_z: mean=-0.02, median=-0.02, sd=0.99, Q1=-0.66, Q3=0.64, NA=0% (n=0) -- New column: GRS_a_z_tri ----------------------------------------------------- GRS_a_z_tri [3 levels] Low: n=60 (20%) Mid: n=180 (60%) High: n=60 (20%) <NA>: n=0 (0%) -- Effect per SD (OR) ---------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z -- v Unadjusted | GRS_a_z: OR 1.10 (0.81-1.49), p = 0.556 v Done: 1 result row across 1 exposure and 1 model. -- High vs Low ----------------------------------------------------------------- ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_logistic -------------------------------------------------------------- i 1 exposure x 1 model = 1 logistic regression i Input cohort: 300 participants | CI method: wald (n/n_cases reflect each model's actual analysis set) -- GRS_a_z_tri -- v Unadjusted | GRS_a_z_triMid: OR 1.00 (0.46-2.19), p = 1 v Unadjusted | GRS_a_z_triHigh: OR 1.25 (0.49-3.16), p = 0.637 v Done: 2 result rows across 1 exposure and 1 model. -- Trend test ------------------------------------------------------------------ ! Exposure GRS_a_z_quad is not an ordered factor -- levels will be scored 0, 1, 2, ... (equal spacing assumed). ! Age and sex adjusted model skipped: age column (UKB field 21022) not found and sex column (UKB field 31) not found. -- assoc_trend ----------------------------------------------------------------- i 1 exposure x 1 model (categorical + trend model per combination) -- GRS_a_z_quad -- i Levels: Q1 -> Q2 -> Q3 -> Q4 | Scores: 0, 1, 2, 3 i Unadjusted | GRS_a_z_quadQ1: 1.00 (ref) v Unadjusted | GRS_a_z_quadQ2: OR 0.90 (0.37-2.20), p = 0.821 v Unadjusted | GRS_a_z_quadQ3: OR 1.54 (0.68-3.50), p = 0.303 v Unadjusted | GRS_a_z_quadQ4: OR 1.00 (0.42-2.39), p = 1 i Unadjusted | trend: OR_per_score = 1.06 (0.81-1.38), p_trend = 0.682 v Done: 4 result rows across 1 exposure and 1 model. -- AUC ------------------------------------------------------------------------- v Validation complete. ! Interrupting test: assoc_logistic() OR > 0, CI spans OR, p in [0,1] Execution halted Flavor: r-devel-linux-x86_64-fedora-gcc

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