Interactive Feature-Based Analysis of AIRR-Seq Data R package AbSolution version 1.0.0 An interactive framework for the exploration and analysis of adaptive immune receptor repertoire sequencing (AIRR-seq) data. It enables large-scale computation and integrated analysis of sequence-derived features, including physicochemical properties, amino acid descriptor sets, sequence motifs, compositional patterns, and somatic hypermutation metrics. The application supports multiscale analysis across sequences, clones, and repertoires, with interactive visualizations and statistical feature selection. 'AbSolution' also facilitates reproducible research by enabling structured export of data, code, parameters, and computational environments. See <https://github.com/EDS-Bioinformatics-Laboratory/AbSolution> for more details. Software Depends: R (>= 4.4.0) Imports: alakazam, attachment, benchmarkme, bigassertr, bigparallelr, bigstatsr, Biostrings, bs4Dash, callr, colourpicker, config (>= 0.3.2), dashboardthemes, data.table, dockerfiler, doParallel, dplyr, DT, foreach, fresh, fs, ggplot2, golem (>= 0.4.1), grDevices, htmlwidgets, IRanges, iterors, knitr, parallel, Peptides, plotly, pwalign, reactable, rlang, rmarkdown, seqinr, shiny (>= 1.7.4), shinycssloaders, shinyFiles, shinyjs, shinymanager, shinymeta, shinythemes, shinyWidgets, sortable, stats, stringdist, stringr, sunburstR, tools, umap, upsetjs, utils, viridis, xfun Suggests: testthat (>= 3.0.0) Rodrigo García-Valiente <r.garciavaliente@amsterdamumc.nl> Comprehensive R Archive Network (CRAN) Rodrigo García-Valiente [cre, aut] (ORCID: <https://orcid.org/0000-0003-0444-5587>, email2: rodrigo.garcia.valiente+absolution@email.com), Charisios Triantafyllou [aut] (ORCID: <https://orcid.org/0000-0002-0283-141X>), Antoine van Kampen [aut, ths] (ORCID: <https://orcid.org/0000-0003-1025-7232>) GPL (>= 3) 2026-04-21 application/tgz https://CRAN.R-project.org/package=AbSolution doi:10.32614/CRAN.package.AbSolution en-US