Toolkit for Clinical, Metabolic, and Cardiovascular Biomarker Calculations R package HealthMarkers version 0.1.2 Computes over 50 specialist health marker functions covering insulin sensitivity and resistance indices (fasting, oral glucose tolerance test, adipose-tissue, tracer, and dual-energy X-ray absorptiometry (DXA)-based), glycaemic and lipid markers, atherogenic and metabolic syndrome scores, liver steatosis and fibrosis scores, and cardiovascular risk algorithms (Framingham Heart Study equations, atherosclerotic cardiovascular disease (ASCVD) Pooled Cohort Equations, the QRISK3 cardiac risk score, and Systematic Coronary Risk Evaluation 2 (SCORE2) including the Older Persons variant (SCORE2-OP)). Also implements renal function (estimated glomerular filtration rate (eGFR), Kidney Failure Risk Equation (KFRE), chronic kidney disease (CKD) staging), pulmonary function (spirometry z-scores, Body-mass index, airflow Obstruction, Dyspnea, and Exercise capacity index (BODE)), inflammatory markers and the inflammatory age clock (iAge), hormonal panels, body composition and anthropometric z-scores, bone turnover markers and fracture risk (Fracture Risk Assessment Tool (FRAX)), frailty and comorbidity indices (Rockwood, Charlson), psychiatric rating scales, and biomarker panels from alternative biofluids (urine, saliva, sweat). Missing value imputation helpers, pre or post computation normalization and a unified all_health_markers() dispatcher that returns all requested marker groups as a single wide tibble are included. Software Depends: R (>= 4.0) Imports: dplyr (>= 1.0.0), rlang (>= 1.0.0), stats, tibble (>= 3.0.0), utils, vctrs, Rdpack Suggests: knitr, rmarkdown, testthat (>= 3.0.0), pkgload, CVrisk, di, rspiro, PooledCohort, QRISK3, RiskScorescvd, usethis, withr, mice, missForest Sufyan Suleman <sufyansuleman@hotmail.com> Comprehensive R Archive Network (CRAN) Sufyan Suleman [aut, cre] (ORCID: <https://orcid.org/0000-0001-6612-6915>) MIT + file LICENSE (https://CRAN.R-project.org/package=HealthMarkers/LICENSE) 2026-05-19 application/tgz https://CRAN.R-project.org/package=HealthMarkers doi:10.32614/CRAN.package.HealthMarkers en-US