Substitution matrices are important parameters in protein alignment algorithms. These matrices represent the likelihood that an amino acid will be substituted for another during mutation. This tool allows users to apply predefined and custom matrices and then explore the resulting alignments with interactive visualizations.  'SubVis' requires the availability of a web browser.

Quality control charts for survival outcomes.
    Allows users to construct the Continuous Time Generalized
    Rapid Response CUSUM (CGR-CUSUM) <doi:10.1093/biostatistics/kxac041>, 
    the Biswas & Kalbfleisch (2008)  <doi:10.1002/sim.3216> CUSUM, 
    the Bernoulli CUSUM and the risk-adjusted funnel plot for survival data 
    <doi:10.1002/sim.1970>. 
    These procedures can be used to monitor survival processes for a change 
    in the failure rate.

Interface to 'Sudachi' <https://github.com/WorksApplications/Sudachi>,
    a Japanese morphological analyzer. This is a port of what is available in Python.

Identify sudden gains based on the three criteria outlined by Tang and DeRubeis (1999) <doi:10.1037/0022-006X.67.6.894> to a selection of repeated measures. Sudden losses, defined as the opposite of sudden gains can also be identified. Two different datasets can be created, one including all sudden gains/losses and one including one selected sudden gain/loss for each case. It can extract scores around sudden gains/losses. It can plot the average change around sudden gains/losses and trajectories of individual cases.

Generates, plays, and solves Sudoku puzzles.  The GUI
        playSudoku() needs package "tkrplot" if you are not on Windows.

Tools for making, retrieving, displaying and solving sudoku games.
    This package is an alternative to the earlier sudoku-solver package,
    'sudoku'.  The present package uses a slightly different algorithm, has a
    simpler coding and presents a few more sugar tools, such as plot and print
    methods.  Solved sudoku games are of some interest in Experimental Design
    as examples of Latin Square designs with additional balance constraints.