The hardware and bandwidth for this mirror is donated by METANET, the Webhosting and Full Service-Cloud Provider.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]metanet.ch.
AHTauDesign 1.0
Major update
- Expanded AHTauDesign from truncation-time assessment to prospective
trial planning for average hazard estimands.
- Added null calibration and support-rule freezing.
- Added
simulate_design() as a public interface for
generating simulation results.
- Implemented Stage 1 support audits and conditional Stage 2 horizon
selection.
- Added independent evaluation of selected planning alternatives.
- Added Part II reverse design with coarse search, fine localization,
and independent validation.
- Added auditable planning reports.
API changes
- Replaced the earlier
assess_tau(),
optimize_tau(), and twostage_tau() workflow
with the new planning interfaces.
- Removed legacy IR outputs from Stage 2.
- Standardized the signed power comparison as
power_difference.
- Added input validation and expanded automated testing.
Important notes
- Information support and statistical power are evaluated
separately.
- A supported clinical horizon is retained.
- Alternative horizons are considered only after Stage 1 support
failure.
- Support-rule thresholds require setting-specific calibration or
validation.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.