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ASSISTant is a package to assist in performing
Adaptive Subgroup
Selection In
Sequential Trials.
ASSISTant provides a three-stage adaptive group
sequential clinical trial design with provision for selecting a subgroup
where the treatment may be effective. The package provides facilities
for design, exploration and analysis of such trials using either
continuous or discrete outcomes. A complete implementation of the
initial design for the DEFUSE-3 trial is also provided as a
vignette.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.