The hardware and bandwidth for this mirror is donated by METANET, the Webhosting and Full Service-Cloud Provider.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]metanet.ch.
Performs genomic mediation analysis with adaptive confounding adjustment (GMAC) proposed by Yang et al. (2017) <doi:10.1101/078683>. It implements large scale mediation analysis and adaptively selects potential confounding variables to adjust for each mediation test from a pool of candidate confounders. The package is tailored for but not limited to genomic mediation analysis (e.g., cis-gene mediating trans-gene regulation pattern where an eQTL, its cis-linking gene transcript, and its trans-gene transcript play the roles as treatment, mediator and the outcome, respectively), restricting to scenarios with the presence of cis-association (i.e., treatment-mediator association) and random eQTL (i.e., treatment).
| Version: | 3.1 |
| Depends: | parallel |
| Published: | 2022-03-17 |
| DOI: | 10.32614/CRAN.package.GMAC |
| Author: | Fan Yang, Jiebiao Wang and Lin Chen |
| Maintainer: | Jiebiao Wang <randel.wang at gmail.com> |
| License: | GPL-2 | GPL-3 [expanded from: GPL] |
| NeedsCompilation: | no |
| CRAN checks: | GMAC results |
| Reference manual: | GMAC.pdf |
| Package source: | GMAC_3.1.tar.gz |
| Windows binaries: | r-devel: GMAC_3.1.zip, r-release: GMAC_3.1.zip, r-oldrel: GMAC_3.1.zip |
| macOS binaries: | r-release (arm64): GMAC_3.1.tgz, r-oldrel (arm64): GMAC_3.1.tgz, r-release (x86_64): GMAC_3.1.tgz, r-oldrel (x86_64): GMAC_3.1.tgz |
| Old sources: | GMAC archive |
Please use the canonical form https://CRAN.R-project.org/package=GMAC to link to this page.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.