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Detects high variance signals and generates dose-response curves to further investigate candidate signals from MALDI cell based assays. More information in Unger et. Al. 2021
The main function in this package is fitCurve() which
will not only do logistic regression and variance filtering but also
handle all preprocessing necessary: - Spectral alignment (“single-point
re-calibration”). - Normalization by an internal standard or known
endogenous signal
All these function can also be called on there own.
This package makes heavy use of the MALDIquant
framework.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.