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A causal mediation approach under the counterfactual framework to test the significance of total, direct and indirect effects. In this approach, a group of methylated sites from a predefined region are utilized as the mediator, and the functional transformation is used to reduce the possible high dimension in the region-based methylated sites and account for their location information.
| Version: | 1.0.1 |
| Depends: | R (≥ 3.5.0), fda |
| Imports: | MASS, stats |
| Published: | 2020-12-17 |
| DOI: | 10.32614/CRAN.package.MRmediation |
| Author: | Qi Yan |
| Maintainer: | Qi Yan <qy2253 at cumc.columbia.edu> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | MRmediation results |
| Reference manual: | MRmediation.pdf |
| Package source: | MRmediation_1.0.1.tar.gz |
| Windows binaries: | r-devel: MRmediation_1.0.1.zip, r-release: MRmediation_1.0.1.zip, r-oldrel: MRmediation_1.0.1.zip |
| macOS binaries: | r-release (arm64): MRmediation_1.0.1.tgz, r-oldrel (arm64): MRmediation_1.0.1.tgz, r-release (x86_64): MRmediation_1.0.1.tgz, r-oldrel (x86_64): MRmediation_1.0.1.tgz |
| Old sources: | MRmediation archive |
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