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changes in version 1.2.1

• Enhancements

  • phase2.TTE() replaces and combines the functionality of Optimal.KJ() and Optimal.rKJ() in previous versions. In addition to the optimal method, this new function also provides designs for single-arm phase II survival trials using the minmax and admissible methods.

  • Sim() replaces and combines the functionality of Sim_KJ() and Sim_rKJ() in previous versions.

  • Examples about how to use phase2.TTE() and Sim() are provided in the vignette and help documentations.

changes in version 1.1.5

• Enhancements
  • for Optimal.KJ() and Optimal.rKJ(), now users can choose to specify a minimum value for the early stopping probability under H0 using the argument prStop. Examples about how to implement this new feature are provided in the vignettes and help documentations.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.