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On CRAN 2021-11-20
df for n2>0 in
sampleN2.TOST() fixed.On CRAN 2021-01-16.
.Machine $double.eps if rho
±1 in power.tsd.2m() to prevent error in
rWishart().min.n2 introduced in
power.tsd.p().session_info()
added.min.n2 in man-pages of
power.tsd() and power.tsd.fC() more correctly
explained.interim.2stage.in() if n1 <3 and
final.tsd.in() if n1 | n2 <3 (avoids errors and
warnings).*.tsd.in() corr.interim.tsd.in() and
power.tsd.in().On CRAN 2019-04-21.
Maintenance release with mainly bug fixes.
final.tsd.in().power.tsd.GS() regarding variable hw.interim.tsd.in() w.r.t to power > target triggering
futility fixed (THX to mittyri).*.tds.in()).On CRAN 2018-04-03.
interim.2stage.in() and
final.2stage.in() to perform interim and final analyses of
2 stage designs based on the Standard Combination or Maximum Combination
Test (also includes a print class).xyz.2stage.ab() now have an alias
xyz.tsd.ab(), e.g. instead of
power.2stage.fC() one may use power.tsd.fC().
The versions with .2stage. in their names will be removed
in later versions.power.2stage.GS() is now
based on the 90% CI to be in line with the other functions using such a
futility rule.fCrit in
power.2stage.GS() changed to "CI".power.2stage.in() in order to be
consistent with paper of Maurer et al (2018).power.tsd.xyz introduced (not public yet).power.tsd.2m() to deal with 2 PK
metrics in the TSD decision scheme Potvin “B” (not public yet).On CRAN 2017-10-27.
sampleN2.TOST() to estimate
n2 in 2x2 and parallel designs based on df=n-3
in stage 2.n-3 for
Potvin like TSD schemes (pooled evaluation with additionally stage
term).power.2Stage.ssr().power.2stage.in() to calculate the operational
characteristics of TSDs evaluated via p-value combination using the
inverse normal approach. Contributed by Benjamin Lang.On CRAN 2017-01-18.
Maintenance release to reflect changes in power calculation of package PowerTOST.
power.2stage.p() and
power.2stage.pAF() removed which caused negative residual
variances in case of test="anova" and imprecise power
values in all other cases for certain scenarios of n1, CV.Internal only 2016-01-21 (not released via CRAN).
"B0" (re)introduced in
power.2stage() and power.2stage.fC() which
employs the decision scheme of the so-called MSDBE (Modified Sequential
Design for BE) of Zheng et al."B" in power.2stage.p() and
power.2stage.pAF() also adapted todecision scheme E of Xu
et al./doc
subdirectory.On CRAN 2015-11-24.
power2stage.fC() has a new argument max.n
which constraints the total sample size."B" in power2stage.fC() and
power.2stage() redefined to deal with unequal
alpha[1] and alpha[2] in the same manner as
method E in Xu et al.This gives small differences compared to previous
calculations with unequal alphas, f.i. Haybittle-Peto alphas.1-2*alpha[1] CI."CI" with a lower
bound 0.925.print argument removed from all
power.2stage.xyz() functions.On CRAN 2015-07-13.
power.2stage.ssr() which prevented
correct sample-size re-estimation if power was calculated via
pmethod="ls".usePE in power.2stage.ssr()
to use the point estimate from the interim analysis in sample-size
re-estimation (makes only sense if blind=FALSE).On CRAN 2015-06-19.
power.2stage.xyz() functions wich
now return an S3 object of class "pwrtsd". Output is now
done more R-like via the S3 print method for class
"pwrtsd". Therefore, the print argument is
defunc and will be removed in the next version.power.2stage.xyz() functions (except
power.2stage.GS()) return a component ntable,
a ‘table’ object for summarizing the discrete distribution of
ntotal. The nhist component was removed.fClower in case of
fCrit="PE" changed to 0.8 in function
power.2stage.fC().detail has now the default
FALSE. Thus be patient if you simulate for alpha with 1 mio
sim’s.nsims argument, if missing, is now set to 1E6 if
you simulate for alpha (i.e. with theta0 at border or
outside acceptance range theta1 ... theta2) and to 1E5
otherwise.Released to alpha testers only 2015-06-10.
power.2stage.yy() functions (except
power.2stage.GS()) now return a component
nhist with class "histogram" which can be used
with plot() to visualize the distribution of
Ntotal. Suggested by H. Schuetz.power.2stage.p() in case of Welch’s test changed (mo more
truncation)."shifted" implemented in
power.2stage.fC().On CRAN 2015-01-24 (dedicated to my brother Stefan’s 50 birthday).
usePE=TRUE).power.2stage.p() accepts now unbalanced stage 1 and
uses the correct power of Welch’s test in the power monitoring steps and
in sample size estimation.power.2stage.p() now available as
power.2stage.pAF() which performs the calculations exactly
as described in Fuglsang’s paper.On CRAN 2014-12-08.
Released to alpha-testers only 2014-12-06 (dedicated to my daughter Antje’s 40 birthday).
power.2stage.Bf() removed.power.2stage() and
power.2stage.fC() have now an argument min.n2
to restrict the sample size of stage 2 to a lower limit.power.2stage.ssr() for (blinded) sample size
re-estimation added (2-stage design without BE decision at
interim).On CRAN 2014-10-09.
power.2stage.Bf() reworked into the new function
power.2stage.fC() to include Potvin method “C” and to
include an additional futility criterion for the CI as well.
power.2stage.Bf() is deprecated and will not be removed in
one of the next versions. Use power.2stage.fC()
instead.On CRAN 2014-07-24.
power.2stage.GS() removed which prevented the
convergence of power values with increasing number of sim’s.On CRAN 2014-07-02.
theta0 close to 1."shifted" added in
power.2stage() to the provide comparison with Potvin et
al.Not released to the public (special version to alpha testers)
On CRAN 2014-05-08.
Released to alpha testers 2014-04-24.
power.2stage.p() for calculation of power
in BE studies with sequential (2-stage) designs in 2 parallel groups
acc. to Fuglsang.On CRAN 2014-04-11.
power.2stage.KM() removed if using
method="B" (Karalis TSD-2). Thanks to Helmut Schuetz!power.2stage.KM() changed to the correct
definition of the Karalis/Macheras TSD or Karalis TSD-1, TSD-2
respectively. # Power2Stage 0.0-7 On CRAN 2014-02-13. Maintenance
release to reflect changes in PowerTOST V1.1-10.power.2stage.GS() for non-adaptive group
sequential (2-stage) BE studies.On CRAN 2014-01-02.
First attempt to release via CRAN 2013-12-27.
Not released, internal version only 2013-09-12.
power.2stage.KM() changed to
"C".power.2stage.KM() removed which are not
necessary for the TSDs described in the Karalis & Macheras and in
Karalis papers (see references).power2.2stage() renamed to
power.2stage.KM().power.2stage.Bf() implemented which
evaluates a 2-stage design derived from Potvin method B with a futility
criterion for the PE of stage 1.Released to alpha testers 2013-09-03.
power2.2stage() implemented which uses PE
and MSE of stage 1 also for the power calculation steps if
usePE=TRUE.Released to alpha testers 2013-07-10.
usePE=FALSE. THX
to Helmut.npct argument changed to
c(0.05, 0.5, 0.95) in accordance with the Potvin
papers.First release to alpha testers 2013-07-09.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.