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QuICSeedR is a comprehensive R package for analyzing and visualizing data from fluorophore-assisted seed amplification assays, such as Real-Time Quaking-Induced Conversion (RT-QuIC) and fluorophore-assisted Protein Misfolding Cyclic Amplification (PMCA). This toolkit addresses limitations in existing software by automating data processing, supporting large-scale analysis, and enabling comparative studies of analysis methods.
You can install the development version of QuICSeedR from GitHub with:
# install.packages("devtools")
devtools::install_github("mancili/QuICSeedR")For more detailed examples and function documentation, please refer to the function help pages. The manuscript link will be added here once it becomes available.
This R package for analyzing seed amplification assay data is available under a dual licensing model: it is freely available under the GNU General Public License v3.0 (GPL-3) for open-source use, and a separate commercial LICENSE is offered for use cases that require additional rights or support beyond the scope of GPL-3.
Manci Li, PhD
ORCID: 0000-0003-3930-7117
If you use QuICSeedR in your research, please cite it as follows:
Li, M. (2024). QuICSeedR: Data analysis for fluorophore-assisted seed amplification assays. R package version 0.1.2. https://github.com/mancili/QuICSeedRFor questions and feedback, please contact Dr. Manci Li at li000021@umn.edu.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.