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RNentropy 1.3.3

• RN_iso_calc and RNentropy_iso_switch no longer return res, which duplicated gene_status and pv.
• The default gene-level threshold of RN_iso_select (gene_pv) is now 0.05 (previously 0.01).
• Corrected the package citation, which now lists the 2018 Nucleic Acids Research article and the 2021 Methods in Molecular Biology chapter.
• Corrected and completed several help pages: an overview of both analyses in the package help, the exact testability rule of min_expr, cross-references between the isoform-switch functions, fixes to the dataset descriptions, and removal of outdated copies of the source code from the examples.

RNentropy 1.3.2

• RN_iso_select now combines the sample p-values of each TESTED gene into a gene-level p-value with the Simes method and compares it with the threshold, without correction across genes. The threshold argument lpv_t is renamed gene_pv, the method argument and the lpv_adj component are removed, and the gene-level p-values are returned as gene_pv. selected reports the gene-level p-value (ISO_GENE_PV) next to the uncorrected per-sample p-values.
• RN_iso_calc and RNentropy_iso_switch return the per-sample p-values as pv (formerly lpv), with columns named ISO_PV_<sample> (formerly ISO_LPV_<sample>).
• Renamed the sample columns of RN_IsoSwitch_Example_S7 and of the compact S7 example file to plain tissue names (brain, heart, kidney, liver, lung, muscle).

RNentropy 1.3.1

• Added RN_iso_select to apply multiple-testing correction to isoform-switch local p-values and retain genes significant in at least one sample.
• Added runnable file-based examples for the standard and isoform-switch workflows using a shared synthetic regression dataset.

RNentropy 1.3.0

• Initialized the public GitHub development repository from the verified CRAN 1.2.3 release.
• Added continuous integration and repository provenance metadata.
• Added RN_iso_calc and RNentropy_iso_switch for the analysis of isoform switching, with explicit testability information and results validated against the independent C++ implementation.
• Added the complete historical S7 isoform-switch example as the compressed RN_IsoSwitch_Example_S7 package dataset.

RNentropy 1.2.3

• Fixed small bug in .RN_design_check preventing compatibility with R >=4.2.0
• Added reference to new publication
• Removed unneeded initialization of .Random.seed
• Fixed a few typos in the documentation
• Added README.md, NEWS.md, and cran-comments.md files

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.