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SMASH: Subclone Multiplicity Allocation and Somatic Heterogeneity

Cluster user-supplied somatic read counts with corresponding allele-specific copy number and tumor purity to infer feasible underlying intra-tumor heterogeneity in terms of number of subclones, multiplicity, and allocation (Little et al. (2019) <doi:10.1186/s13073-019-0643-9>).

Version: 1.0.0
Depends: R (≥ 2.10)
Imports: Rcpp, stats, smarter, reshape2, ggplot2
LinkingTo: Rcpp, RcppArmadillo
Suggests: knitr, devtools
Published: 2025-02-27
DOI: 10.32614/CRAN.package.SMASH
Author: Paul Little [aut, cre]
Maintainer: Paul Little <pllittle321 at gmail.com>
License: GPL (≥ 3)
NeedsCompilation: yes
Citation: SMASH citation info
CRAN checks: SMASH results

Documentation:

Reference manual: SMASH.pdf
Vignettes: test (source, R code)

Downloads:

Package source: SMASH_1.0.0.tar.gz
Windows binaries: r-devel: SMASH_1.0.0.zip, r-release: SMASH_1.0.0.zip, r-oldrel: SMASH_1.0.0.zip
macOS binaries: r-devel (arm64): SMASH_1.0.0.tgz, r-release (arm64): SMASH_1.0.0.tgz, r-oldrel (arm64): SMASH_1.0.0.tgz, r-devel (x86_64): SMASH_1.0.0.tgz, r-release (x86_64): SMASH_1.0.0.tgz, r-oldrel (x86_64): SMASH_1.0.0.tgz

Linking:

Please use the canonical form https://CRAN.R-project.org/package=SMASH to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.