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dtlcor: Multiplicity Control on Drop-the-Losers Designs

A tool to calculate the correlation boundary for the correlation between the response rate and the log-rank test statistic for the binary surrogate endpoint and the time-to-event primary endpoint, as well as conduct simulation studies to obtain design operating characteristics of the drop-the-losers design.

Version: 0.1.0
Depends: shiny, shinythemes, ggplot2
Imports: survival, stringr, DT, gsDesign, coin, dplyr, stats, tidyr, mvtnorm, cubature
Published: 2025-05-19
DOI: 10.32614/CRAN.package.dtlcor
Author: Weibin Zhong [aut, cre], Jing-ou Liu [aut], chenguang Wang [aut]
Maintainer: Weibin Zhong <wzhong3 at gmu.edu>
License: GPL (≥ 3)
NeedsCompilation: no
Materials: README
CRAN checks: dtlcor results

Documentation:

Reference manual: dtlcor.pdf

Downloads:

Package source: dtlcor_0.1.0.tar.gz
Windows binaries: r-devel: dtlcor_0.1.0.zip, r-release: dtlcor_0.1.0.zip, r-oldrel: not available
macOS binaries: r-release (arm64): dtlcor_0.1.0.tgz, r-oldrel (arm64): dtlcor_0.1.0.tgz, r-release (x86_64): dtlcor_0.1.0.tgz, r-oldrel (x86_64): dtlcor_0.1.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.