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escalation 0.1.10

• Added TITE methods

escalation 0.1.9

• Fixed inheritance problems with as_tibble, summary and print dose_selector generics
• Added many tests of dose_selector consistency.

escalation 0.1.8

• Made tests faster for CRAN

escalation 0.1.7

• Added ability to import and export PatientSamples
• Split the simulation vignette

escalation 0.1.6

• Implement efficient simulation comparison method of Sweeting et al. in simulate_compare()
• Implement BOIN12 design
• Add MTD / OBD selectors for TPI, mTPI, mTPI2 and BOIN12 for final dose choice at end of a trial

escalation 0.1.5

• Add mTPI2 dose-finding method
• Fixed some bugs

escalation 0.1.4

• Added Neuenschwander, Branson & Sponer’s method for phase I.
• Added Ji et al.’s TPI & mTI methods for phase I.
• Added Thall & Cook’s EffTox method for phase I/II.
• Added Wages & Tait’s method for phase I/II.

escalation 0.1.3

• Mainly small changes to comply with dplyr v1.0.
• simulations and crystallised_dose_paths given summary method
• NOTE squash

escalation 0.1.2

• Methods for simulation and calculating dose-paths added.
• A bit more on the general selector interface.
• Everything new has tests, and more tests on old stuff.

escalation 0.1.1

• Initial release.
• dfcrm, BOIN, 3+3 models supported.
• several objects included to facilitate stopping at different events.
• class for a fixed escalation plan included, as sometimes used with CRM.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.