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The goal of {hgnc} is to easily import Human Gene Nomenclature into R.
Install {hgnc} from CRAN:
install.packages("hgnc")To import the latest HGNC gene data set in tabular format directly into memory as a tibble do as follows:
library(hgnc)
# Check the date of HGNC last update
last_update()
#> [1] "2025-06-17 11:10:30 UTC"
# Import the data set in tidy tabular format
(hgnc_dataset <- import_hgnc_dataset())
#> # A tibble: 44,117 × 55
#> hgnc_id hgnc_id2 symbol name locus_group locus_type status location
#> <chr> <int> <chr> <chr> <chr> <chr> <chr> <chr>
#> 1 HGNC:5 5 A1BG alpha-1… protein-co… gene with… Appro… 19q13.43
#> 2 HGNC:37133 37133 A1BG-AS1 A1BG an… non-coding… RNA, long… Appro… 19q13.43
#> 3 HGNC:24086 24086 A1CF APOBEC1… protein-co… gene with… Appro… 10q11.23
#> 4 HGNC:7 7 A2M alpha-2… protein-co… gene with… Appro… 12p13.31
#> 5 HGNC:27057 27057 A2M-AS1 A2M ant… non-coding… RNA, long… Appro… 12p13.31
#> 6 HGNC:23336 23336 A2ML1 alpha-2… protein-co… gene with… Appro… 12p13.31
#> 7 HGNC:41022 41022 A2ML1-AS1 A2ML1 a… non-coding… RNA, long… Appro… 12p13.31
#> 8 HGNC:41523 41523 A2ML1-AS2 A2ML1 a… non-coding… RNA, long… Appro… 12p13.31
#> 9 HGNC:8 8 A2MP1 alpha-2… pseudogene pseudogene Appro… 12p13.31
#> 10 HGNC:30005 30005 A3GALT2 alpha 1… protein-co… gene with… Appro… 1p35.1
#> # ℹ 44,107 more rows
#> # ℹ 47 more variables: location_sortable <chr>, alias_symbol <list>,
#> # alias_name <list>, prev_symbol <list>, prev_name <list>, gene_group <list>,
#> # gene_group_id <list>, date_approved_reserved <date>,
#> # date_symbol_changed <date>, date_name_changed <date>, date_modified <date>,
#> # entrez_id <chr>, ensembl_gene_id <chr>, vega_id <chr>, ucsc_id <chr>,
#> # ena <list>, refseq_accession <list>, ccds_id <list>, uniprot_ids <list>, …Learn more about this package by reading the documentation at https://www.pattern.institute/hgnc/.
To cite HGNC nomenclature resources use:
To cite data within the database use the following format:
Please include the month and year you retrieved the data cited.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.