imputeLCMD: A Collection of Methods for Left-Censored Missing Data Imputation

A collection of functions for left-censored missing data imputation. Left-censoring is a special case of missing not at random (MNAR) mechanism that generates non-responses in proteomics experiments. The package also contains functions to artificially generate peptide/protein expression data (log-transformed) as random draws from a multivariate Gaussian distribution as well as a function to generate missing data (both randomly and non-randomly). For comparison reasons, the package also contains several wrapper functions for the imputation of non-responses that are missing at random. * New functionality has been added: a hybrid method that allows the imputation of missing values in a more complex scenario where the missing data are both MAR and MNAR.

Version:	2.1
Depends:	R (≥ 2.10), tmvtnorm, norm, pcaMethods, impute
Published:	2022-06-10
DOI:	10.32614/CRAN.package.imputeLCMD
Author:	Cosmin Lazar [aut], Thomas Burger [aut], Samuel Wieczorek [cre, ctb]
Maintainer:	Samuel Wieczorek <samuel.wieczorek at cea.fr>
License:	GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation:	no
In views:	MissingData, Omics
CRAN checks:	imputeLCMD results

Documentation:

Reference manual:

imputeLCMD.pdf

Downloads:

Package source:	imputeLCMD_2.1.tar.gz
Windows binaries:	r-devel: imputeLCMD_2.1.zip, r-release: imputeLCMD_2.1.zip, r-oldrel: imputeLCMD_2.1.zip
macOS binaries:	r-release (arm64): imputeLCMD_2.1.tgz, r-oldrel (arm64): imputeLCMD_2.1.tgz, r-release (x86_64): imputeLCMD_2.1.tgz, r-oldrel (x86_64): imputeLCMD_2.1.tgz
Old sources:	imputeLCMD archive

Reverse dependencies:

Reverse imports:	DEP, lipidr, MatrixQCvis, rexposome
Reverse suggests:	MsCoreUtils, msImpute, MSnbase, QFeatures, qmtools

Linking:

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