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Implements Mander & Thompson's (2010) <doi:10.1016/j.cct.2010.07.008> methods for two-stage designs optimal under the alternative hypothesis for phase II [cancer] trials. Also provides an implementation of Simon's (1989) <doi:10.1016/0197-2456(89)90015-9> original methodology and allows exploration of the operating characteristics of sub-optimal designs.
Version: | 0.1.0 |
Imports: | dplyr, ggplot2, logger, magrittr, methods, Rcpp, rlang, tibble, tidyr |
LinkingTo: | Rcpp, BH |
Suggests: | covr, parallel, testthat (≥ 3.0.0) |
Published: | 2022-10-27 |
DOI: | 10.32614/CRAN.package.mtdesign |
Author: | John Kirkpatrick |
Maintainer: | John Kirkpatrick <john.kirkpatrick at roche.com> |
BugReports: | https://github.com/openpharma/mtdesign/issues |
License: | GPL (≥ 3) |
URL: | https://github.com/openpharma/mtdesign |
NeedsCompilation: | yes |
Language: | en-GB |
Materials: | README NEWS |
CRAN checks: | mtdesign results |
Reference manual: | mtdesign.pdf |
Package source: | mtdesign_0.1.0.tar.gz |
Windows binaries: | r-devel: mtdesign_0.1.0.zip, r-release: mtdesign_0.1.0.zip, r-oldrel: mtdesign_0.1.0.zip |
macOS binaries: | r-release (arm64): mtdesign_0.1.0.tgz, r-oldrel (arm64): mtdesign_0.1.0.tgz, r-release (x86_64): mtdesign_0.1.0.tgz, r-oldrel (x86_64): mtdesign_0.1.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.