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Functions to calculate estimates of intrinsic and extrinsic noise from the two-reporter single-cell experiment, as in Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186. Functions implement multiple estimators developed for unbiasedness or min Mean Squared Error (MSE) in Fu, A. Q. and Pachter, L. (2016). Estimating intrinsic and extrinsic noise from single-cell gene expression measurements. Statistical Applications in Genetics and Molecular Biology, 15(6), 447-471.
Version: | 1.0.2 |
Depends: | R (≥ 2.10) |
Imports: | preprocessCore |
Published: | 2024-02-29 |
DOI: | 10.32614/CRAN.package.noise |
Author: | Audrey Qiuyan Fu and Lior Pachter |
Maintainer: | Audrey Q. Fu <audreyqyfu at gmail.com> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
NeedsCompilation: | no |
CRAN checks: | noise results |
Reference manual: | noise.pdf |
Package source: | noise_1.0.2.tar.gz |
Windows binaries: | r-devel: noise_1.0.2.zip, r-release: noise_1.0.2.zip, r-oldrel: noise_1.0.2.zip |
macOS binaries: | r-release (arm64): noise_1.0.2.tgz, r-oldrel (arm64): noise_1.0.2.tgz, r-release (x86_64): noise_1.0.2.tgz, r-oldrel (x86_64): noise_1.0.2.tgz |
Old sources: | noise archive |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.