opentimsr: An Open-Source Loader for Bruker's timsTOF Data Files

Reads raw data from Bruker's timsTOF mass spectrometers, stored in analysis.tdf and analysis.tdf_bin files inside .d folders. Frames can be selected by number or by retention time, and each peak is reported with its scan, time-of-flight index, intensity, mass-to-charge ratio and inverse ion mobility. Mass-to-charge ratios and ion mobilities are computed with built-in open-source calibration, or optionally with Bruker's proprietary library. See Łącki et al. (2021) <doi:10.1021/acs.jproteome.0c00962>.

Version:	1.2.0
Depends:	R (≥ 4.3.0)
Imports:	Rcpp (≥ 0.12.0), methods, DBI, RSQLite
LinkingTo:	Rcpp
Suggests:	testthat (≥ 3.0.0)
Published:	2026-10-22
DOI:	10.32614/CRAN.package.opentimsr (may not be active yet)
Author:	Michał Piotr Startek [aut, cph], Mateusz Krzysztof Łącki [aut, cre, cph], mandreyel [ctb, cph] (Author and copyright holder of the bundled 'mio' library (https://github.com/mandreyel/mio))
Maintainer:	Mateusz Krzysztof Łącki <matteo.lacki at gmail.com>
BugReports:	https://github.com/michalsta/opentims/issues
License:	MIT + file LICENSE
Copyright:	See file inst/COPYRIGHTS opentimsr copyright details
URL:	https://github.com/michalsta/opentims
NeedsCompilation:	yes
SystemRequirements:	C++20, libzstd
Citation:	opentimsr citation info
CRAN checks:	opentimsr results [issues need fixing before 2026-11-12]

Documentation:

Reference manual:

opentimsr.html , opentimsr.pdf

Downloads:

Package source:	opentimsr_1.2.0.tar.gz
Windows binaries:	r-devel: not available, r-release: not available, r-oldrel: opentimsr_1.2.0.zip
macOS binaries:	r-release (arm64): opentimsr_1.2.0.tgz, r-oldrel (arm64): opentimsr_1.2.0.tgz, r-release (x86_64): opentimsr_1.2.0.tgz, r-oldrel (x86_64): opentimsr_1.2.0.tgz

Linking:

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