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The goal of PBM is to make analysing Biolayer Interferometry (BLI) or Surface Plasmon Resonance (SPR) data more open. After initial binding parameters are known, binding curves can be simulated and parameters such as: analyte concentration, time of association, dissociation etc. can be varied. The models within this package may also be used to fit a curve to measured binding data using a non-linear regression.
Currently, two binding models are included with this package:
Note: more binding models are on their way.. bivalent model, mass-transport params etc.
Install the released version of usethis from CRAN:
install.packages("pbm")Or install the development version from GitHub with:
install.packages("devtools")
devtools::install_github("jonathanrd/pbm")For usage information and examples, see the vignette and reference manual on CRAN: pbm.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.