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plinkQC 0.3.4
major changes
- Add flag for removing high LD regions and add option for user
provided file, allowing removal of high LD regions for non-human
organisms; fix missing flag 19bc569
and #42
- Fixed failing data.no_failIDs.lmiss file in check_snp_missingness
function when failIDs were present 86adc39
and #43
plinkQC 0.3.3
major changes
- Output all IBD estimates in
run_check_relatedness not
just fail IBD estimates d009da90
- Add midp modifier for –hwe and –hardy as recommended on plink hwe
documentation and discussed in issue #27; 43230a6c
- Provide HapMap and 1000Genomes individual and population identifiers
as default for ancestry check functions; include optional color mapping
for these reference populations; raised in #37,
incorporated in 65cfcba
- for all individual QC functions return data.frame with FID, IID and
measure used for filtering #5
incorporated in 295505b
- allow for user-supplied individual and marker filtering in
perIndividualQC, perMarkerQC and cleanData #33
- individual highlighting in perIndividualQC plots; several highlight
modalities (text/label, shape, color) #38
minor changes
- Add checks in
cleanData that can distinguish between
miss-specified filters and non-failing samples 7432b1ee;
addresses issue #31
- Add checks and tests in
check_snp_missingness,
check_maf and check_hwe in cases where all
samples pass perIndividualQC. 31ed6f65;
related to issue #31
- Add checks and tests in
evaluate_check_sex and
evaluate_check_het_imiss for all passing samples and
accordingly, no fail samples label in plot. d071a43
- Update dropbox links and add note to vignette 9bae988
- additional plotting parameters for
evaluate_*
functions, controlling text and title sizes (b38a348,
f25b8d0)
plinkQC 0.3.2
minor changes
- Add checks and tests in
evaluate_check_ancestry for
missing non-reference samples 5c03971
- Clarified tutorials:
- R internal file.copy instead of systems
cp command to
make run on windows: 6c91ef3,
fixes #26
- Add additional filter for A->T, C->G variants as suggested in
#24;
11e0375
- Fixed plotting issues in PCA plot of ancestry check:
- allow for supplying names of European reference population ae09e64
- provide argument to specify number of populations per legend row c7fe85d
- Ensure correct ordering of population colors when reference
population is not HapMap 86275b7
plinkQC 0.3.1
minor changes
- Fixed dead links in vignettes (caused by migration of repository):
da987d8
- Added note about chrY in Hapmap data (vignette): e8afbb9
- Added note about recommended use of plink1.9 (vs 2.0): b69d3d7
plinkQC 0.3.0
major changes
- Relationship filter can handle more complicated relationship
scenarios as observed in plant genotype sets (fixed #11)
- code moved to the meyer-lab repository:
https://github.com/meyer-lab-cshl/plinkQC
plinkQC 0.2.3
major changes
- Enable return of overview plots as ggplot object (fixes #6 in ab2e840
and 101e74e)
- Relationship filter now deals with more complicated relationship
scenarios as observed in plant genotype sets (addresses #11)
minor changes
- give user option to choose maf threshold for relatedness filtering
(relates to #3)
bug fixes
- Include check for zero related individuals fixing #3 in 1445a88
- Include check in case all samples fail perIndividual QC in 894acc1
and 0464224)
- Include checks for diagonal derived relationship estimates, and
estimate data containing only related individuals; addresses #11
- Fix command for genotype conversion in 1000Genomes vignette,
addressing issue #10
- fix missing rownames error for overviewPerIndividualQC, when
relatedness check was included (issue #16, fc7a38b)
- fix vignette mismatch (issue #16, 09dcd59)
plinkQC 0.2.2
minor changes
- Fix IDs written to fail.IDs file: previous versions wrote IID,IID,
now fixed to FID, IID (fixes #2).
plinkQC 0.2.1
minor changes
- Fix path check bug in checkPlink
- Include test data in build!
plinkQC 0.2.0
major changes
- All system calls to plink are conducted with sys::exec_wait - this
should solve platform dependent issues, mainly compatibility with
windows.
- Make path construction compatible with windows.
- path2plink now requires full path to plink executable, no tilde
expansion or simple pointer to directory supported.
- Fix bug in return of cleanData function: list now contains keep and
fail IDs.
- Fix bug in return of maf computation: if fail.IDs does not exist,
set fail_samples to zero.
minor changes
- IBD-fail.IDs now saved without column names to be consistent with
other xxx-fail.IDs files.
- Include additional progress messages in cleanData()
- Remove default double-specification of mafTh and macTh
- use checkPlink to return correct path2plink and export to make
checkPlink directly accesible to user.
plinkQC 0.1.1
major changes
- run_check_relatedness will only save IBD estimates of individuals
whose estimates are higher than the threshold.
minor changes
- Fix examples in vignettes 1000 Genomes and HapMap III
reference.
- Change file access in function examples
- Add additional checks in check_ancestry and fix missing
refSamplesFile test
plinkQC 0.1.0
- Added a
NEWS.md file to track changes to the
package.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.