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powerHE: Power and Sample Size Calculations with Hierarchical Endpoints

Calculate sample size or power for hierarchical endpoints. The package can handle any type of outcomes (binary, continuous, count, ordinal, time-to-event) and any number of such endpoints. It allows users to calculate sample size with a given power or to calculate power with a given sample size for hypothesis testing based on win ratios, win odds, net benefit, or DOOR (desirability of outcome ranking) as treatment effect between two groups for hierarchical endpoints. The methods of this package are described further in the paper by Barnhart, H. X. et al. (2024, <doi:10.1080/19466315.2024.2365629>).

Version: 1.0.0
Imports: skellam
Published: 2025-02-10
DOI: 10.32614/CRAN.package.powerHE
Author: Sarah Wu [aut, cre], Dylan Thibault [aut]
Maintainer: Sarah Wu <O2E at duke.edu>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: powerHE results

Documentation:

Reference manual: powerHE.pdf

Downloads:

Package source: powerHE_1.0.0.tar.gz
Windows binaries: r-devel: powerHE_1.0.0.zip, r-release: powerHE_1.0.0.zip, r-oldrel: powerHE_1.0.0.zip
macOS binaries: r-devel (arm64): powerHE_1.0.0.tgz, r-release (arm64): powerHE_1.0.0.tgz, r-oldrel (arm64): powerHE_1.0.0.tgz, r-devel (x86_64): powerHE_1.0.0.tgz, r-release (x86_64): powerHE_1.0.0.tgz, r-oldrel (x86_64): powerHE_1.0.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.