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retriever: Generate Disease-Specific Response Signatures from the LINCS-L1000 Data

Generates disease-specific drug-response profiles that are independent of time, concentration, and cell-line. Based on the cell lines used as surrogates, the returned profiles represent the unique transcriptional changes induced by a compound in a given disease.

Version: 0.2.1
Depends: R (≥ 3.5.0)
Imports: pbapply, preprocessCore
Suggests: ccdata
Published: 2021-11-11
DOI: 10.32614/CRAN.package.retriever
Author: Daniel Osorio ORCID iD [aut, cre], Marieke Kuijjer ORCID iD [aut]
Maintainer: Daniel Osorio <daniecos at uio.no>
License: GPL-3
NeedsCompilation: no
Materials: README
CRAN checks: retriever results

Documentation:

Reference manual: retriever.pdf

Downloads:

Package source: retriever_0.2.1.tar.gz
Windows binaries: r-devel: retriever_0.2.1.zip, r-release: retriever_0.2.1.zip, r-oldrel: retriever_0.2.1.zip
macOS binaries: r-release (arm64): retriever_0.2.1.tgz, r-oldrel (arm64): retriever_0.2.1.tgz, r-release (x86_64): retriever_0.2.1.tgz, r-oldrel (x86_64): retriever_0.2.1.tgz
Old sources: retriever archive

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.