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scDiffCom 1.2.0

• run_interaction_analysis() now uses seurat_layer argument instead of seurat_slot to be consistent with Seurat (>= 5.0.0)
• Clean internal data dependencies and remove explicit call to SingleCellSignalR::LRdb
• Fix broken links in README
• Prepare for CRAN submission

scDiffCom 1.1.0

• Allow to use a custom LRI database

scDiffCom 1.0.0

01-11-2023

• Prepare for CRAN release
• Update links to the Nature Aging paper

scDiffCom 0.2.4

11-04-2023

• Change default red-green colors in plots
• Improve README and website

scDiffCom 0.2.3

08-05-2022

• Remove mouse and rat LRIs with “homolog_orthology_confidence” of 0, but only if they are not already provided directly by one of the “source database”
• Remove some miss-curated LRIs

scDiffCom 0.2.2

11-04-2022

• Compute (permutation-based) p-values and logFC for each ligand and receptor gene independently

scDiffCom 0.2.1

20-01-2022

• Fix a bug that appeared when ‘seurat_object[[]]’ contained a column named ‘cell_id’

scDiffCom 0.2.0

24-11-2021

• New function BuildShiny() that creates a shiny app from the results
• New function ReduceGO() to reduce GO terms by semantic similarity

scDiffCom 0.1.0.9000

09-11-2021

• A rat LRI database (LRI_rat) has been added (based on orthology conversion)
• run_interaction_analysis() accepts rat as species parameter
• LRI datasets have a reduced size
• Dataset gene_ontology_level is now available as data (instead of internal data)

scDiffCom 0.1

04-07-2021

• All steps of run_interaction_analysis have been tested
• All exported functions have been tested
• LRI databases have been curated
• Complete roxygen-based documentation
• Vignette contains the main functionalities

scDiffCom 0.0.0.9000

• Added a NEWS.md file to track changes to the package.
• Added the first proper documentation
• Added the first version of the vignette

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.