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If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]metanet.ch.
To cite the SHazaM package in publications, please use:
Gupta N, Vander Heiden J, Uduman M, Gadala-Maria D, Yaari G, Kleinstein S (2015). “Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data.” Bioinformatics, 1-3. doi:10.1093/bioinformatics/btv359.
To cite the selection analysis methods, please use:
Yaari G, Uduman M, Kleinstein S (2012). “Quantifying selection in high-throughput Immunoglobulin sequencing data sets.” Nucleic acids research, 40(17), e134. doi:10.1093/nar/gks457.
To cite the HH_S5F model and the targeting model generation methods, please use:
Yaari G, Vander Heiden J, Uduman M, Gadala-Maria D, Gupta N, Stern J, O'Connor K, Hafler D, Lasserson U, Vigneault F, Kleinstein S (2013). “Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.” Frontiers in Immunology, 4(358), 1-11. doi:10.3389/fimmu.2013.00358.
To cite the HKL_S1F, HKL_S5F, MK_RS1NF, and MK_RS5NF models, please use:
Cui A, Di Niro R, Vander Heiden J, Briggs A, Adams K, Gilbert T, O'Connor K, Vigneault F, Shlomchik M, Kleinstein S (2016). “A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data.” The Journal of Immunology, 197(9), 3566-3574. doi:10.4049/jimmunol.1502263.
Corresponding BibTeX entries:
@Article{, style = {citation}, title = {Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data.}, author = {Namita T. Gupta and Jason A. {Vander Heiden} and Mohamed Uduman and Daniel Gadala-Maria and Gur Yaari and Steven H. Kleinstein}, year = {2015}, journal = {Bioinformatics}, pages = {1-3}, doi = {10.1093/bioinformatics/btv359}, }
@Article{, style = {citation}, title = {Quantifying selection in high-throughput Immunoglobulin sequencing data sets.}, author = {Gur Yaari and Mohamed Uduman and Steven H. Kleinstein}, year = {2012}, journal = {Nucleic acids research}, volume = {40}, number = {17}, pages = {e134}, doi = {10.1093/nar/gks457}, }
@Article{, style = {citation}, title = {Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.}, author = {Gur Yaari and Jason A. {Vander Heiden} and Mohamed Uduman and Daniel Gadala-Maria and Namita T. Gupta and Joel N. H. Stern and Kevin C. O'Connor and David A. Hafler and Uri Lasserson and Francois Vigneault and Steven H. Kleinstein}, year = {2013}, journal = {Frontiers in Immunology}, volume = {4}, number = {358}, pages = {1-11}, doi = {10.3389/fimmu.2013.00358}, }
@Article{, style = {citation}, title = {A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data.}, author = {Ang Cui and Roberto {Di Niro} and Jason A. {Vander Heiden} and Adrian W. Briggs and Kris Adams and Tamara Gilbert and Kevin C. O'Connor and Francois Vigneault and Mark J. Shlomchik and Steven H. Kleinstein}, year = {2016}, journal = {The Journal of Immunology}, volume = {197}, number = {9}, pages = {3566-3574}, doi = {10.4049/jimmunol.1502263}, }
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.