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An R data package containing a list of genes which are frequently mutated in somatic cancer datasets but are unlikely to drive disease
install.packages("somaticflags")library(somaticflags)
# List Gene Names
somaticflags
# Print a dataframe describing the source of each somatic flag
somaticflags_dfIf not using R, you can download our list of somaticflags here
| Gene | Source | Reason |
|---|---|---|
| TTN | 10.1186/s12920-014-0064-y;10.1038/nature12213 | TOP20FLAGS;OTHER |
| MUC16 | 10.1186/s12920-014-0064-y;10.1038/nature12213 | TOP20FLAGS;OTHER |
| OBSCN | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| AHNAK2 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| SYNE1 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| FLG | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| MUC5B | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| DNAH17 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| PLEC | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| DST | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| SYNE2 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| NEB | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| HSPG2 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| LAMA5 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| AHNAK | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| HMCN1 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| USH2A | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| DNAH11 | 10.1186/s12920-014-0064-y;10.1038/nature12213 | TOP20FLAGS;OTHER |
| MACF1 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| MUC17 | 10.1186/s12920-014-0064-y | TOP20FLAGS |
| OR2G6 | 10.1038/nature12213 | OLFACTORY |
| OR4C6 | 10.1038/nature12213 | OLFACTORY |
| OR4M2 | 10.1038/nature12213 | OLFACTORY |
| OR5L2 | 10.1038/nature12213 | OLFACTORY |
| OR2T4 | 10.1038/nature12213 | OLFACTORY |
| OR5D18 | 10.1038/nature12213 | OLFACTORY |
| OR4A15 | 10.1038/nature12213 | OLFACTORY |
| OR6F1 | 10.1038/nature12213 | OLFACTORY |
| OR2T33 | 10.1038/nature12213 | OLFACTORY |
| OR4S2 | 10.1038/nature12213 | OLFACTORY |
| OR11L1 | 10.1038/nature12213 | OLFACTORY |
| OR4M1 | 10.1038/nature12213 | OLFACTORY |
| OR5T1 | 10.1038/nature12213 | OLFACTORY |
| OR8J3 | 10.1038/nature12213 | OLFACTORY |
| OR51B2 | 10.1038/nature12213 | OLFACTORY |
| OR8H2 | 10.1038/nature12213 | OLFACTORY |
| OR9G9 | 10.1038/nature12213 | OLFACTORY |
| OR4N2 | 10.1038/nature12213 | OLFACTORY |
| OR10G9 | 10.1038/nature12213 | OLFACTORY |
| OR5I1 | 10.1038/nature12213 | OLFACTORY |
| OR14A16 | 10.1038/nature12213 | OLFACTORY |
| OR2M2 | 10.1038/nature12213 | OLFACTORY |
| OR5B12 | 10.1038/nature12213 | OLFACTORY |
| OR5M9 | 10.1038/nature12213 | OLFACTORY |
| OR4C11 | 10.1038/nature12213 | OLFACTORY |
| OR1C1 | 10.1038/nature12213 | OLFACTORY |
| OR4N4 | 10.1038/nature12213 | OLFACTORY |
| OR5J2 | 10.1038/nature12213 | OLFACTORY |
| OR2G3 | 10.1038/nature12213 | OLFACTORY |
| OR10G8 | 10.1038/nature12213 | OLFACTORY |
| OR5W2 | 10.1038/nature12213 | OLFACTORY |
| OR2T3 | 10.1038/nature12213 | OLFACTORY |
| OR10AG1 | 10.1038/nature12213 | OLFACTORY |
| OR4K1 | 10.1038/nature12213 | OLFACTORY |
| OR2M7 | 10.1038/nature12213 | OLFACTORY |
| OR4C12 | 10.1038/nature12213 | OLFACTORY |
| OR4D5 | 10.1038/nature12213 | OLFACTORY |
| OR2T1 | 10.1038/nature12213 | OLFACTORY |
| OR4P4 | 10.1038/nature12213 | OLFACTORY |
| OR5H14 | 10.1038/nature12213 | OLFACTORY |
| OR5F1 | 10.1038/nature12213 | OLFACTORY |
| OR2T8 | 10.1038/nature12213 | OLFACTORY |
| OR4C13 | 10.1038/nature12213 | OLFACTORY |
| OR5K1 | 10.1038/nature12213 | OLFACTORY |
| OR4K5 | 10.1038/nature12213 | OLFACTORY |
| OR2B11 | 10.1038/nature12213 | OLFACTORY |
| OR5L1 | 10.1038/nature12213 | OLFACTORY |
| OR2L8 | 10.1038/nature12213 | OLFACTORY |
| OR2T12 | 10.1038/nature12213 | OLFACTORY |
| OR2T34 | 10.1038/nature12213 | OLFACTORY |
| OR8H1 | 10.1038/nature12213 | OLFACTORY |
| OR5D16 | 10.1038/nature12213 | OLFACTORY |
| OR10Q1 | 10.1038/nature12213 | OLFACTORY |
| OR2M3 | 10.1038/nature12213 | OLFACTORY |
| OR6K3 | 10.1038/nature12213 | OLFACTORY |
| OR5T3 | 10.1038/nature12213 | OLFACTORY |
| OR14C36 | 10.1038/nature12213 | OLFACTORY |
| OR5AC2 | 10.1038/nature12213 | OLFACTORY |
| OR52J3 | 10.1038/nature12213 | OLFACTORY |
| OR4Q3 | 10.1038/nature12213 | OLFACTORY |
| OR10A4 | 10.1038/nature12213 | OLFACTORY |
| OR4C16 | 10.1038/nature12213 | OLFACTORY |
| OR8B2 | 10.1038/nature12213 | OLFACTORY |
| OR5D14 | 10.1038/nature12213 | OLFACTORY |
| OR5H6 | 10.1038/nature12213 | OLFACTORY |
| OR8I2 | 10.1038/nature12213 | OLFACTORY |
| OR2T2 | 10.1038/nature12213 | OLFACTORY |
| OR4A16 | 10.1038/nature12213 | OLFACTORY |
| OR52E6 | 10.1038/nature12213 | OLFACTORY |
| OR6N1 | 10.1038/nature12213 | OLFACTORY |
| OR2AK2 | 10.1038/nature12213 | OLFACTORY |
| OR2L2 | 10.1038/nature12213 | OLFACTORY |
| OR4D11 | 10.1038/nature12213 | OLFACTORY |
| OR2A5 | 10.1038/nature12213 | OLFACTORY |
| OR51S1 | 10.1038/nature12213 | OLFACTORY |
| OR9A2 | 10.1038/nature12213 | OLFACTORY |
| OR51L1 | 10.1038/nature12213 | OLFACTORY |
| OR56A4 | 10.1038/nature12213 | OLFACTORY |
| OR52E2 | 10.1038/nature12213 | OLFACTORY |
| OR6M1 | 10.1038/nature12213 | OLFACTORY |
| OR2T11 | 10.1038/nature12213 | OLFACTORY |
| OR5M11 | 10.1038/nature12213 | OLFACTORY |
| OR4C46 | 10.1038/nature12213 | OLFACTORY |
| OR6K2 | 10.1038/nature12213 | OLFACTORY |
| OR2B3 | 10.1038/nature12213 | OLFACTORY |
| OR2T6 | 10.1038/nature12213 | OLFACTORY |
| OR56A1 | 10.1038/nature12213 | OLFACTORY |
| OR5B2 | 10.1038/nature12213 | OLFACTORY |
| OR4K15 | 10.1038/nature12213 | OLFACTORY |
| OR5AS1 | 10.1038/nature12213 | OLFACTORY |
| OR8A1 | 10.1038/nature12213 | OLFACTORY |
| OR4C3 | 10.1038/nature12213 | OLFACTORY |
| OR4D2 | 10.1038/nature12213 | OLFACTORY |
| OR8K3 | 10.1038/nature12213 | OLFACTORY |
| OR8J1 | 10.1038/nature12213 | OLFACTORY |
| OR4F6 | 10.1038/nature12213 | OLFACTORY |
| OR8H3 | 10.1038/nature12213 | OLFACTORY |
| OR1J4 | 10.1038/nature12213 | OLFACTORY |
| OR52A5 | 10.1038/nature12213 | OLFACTORY |
| OR8B4 | 10.1038/nature12213 | OLFACTORY |
| OR51I1 | 10.1038/nature12213 | OLFACTORY |
| OR2T33 | 10.1038/nature12213 | OLFACTORY |
| CSMD3 | 10.1038/nature12213 | OTHER |
| CNTNAP5 | 10.1038/nature12213 | OTHER |
| RYR2 | 10.1038/nature12213 | OTHER |
| LRP1B | 10.1038/nature12213 | OTHER |
| CSMD1 | 10.1038/nature12213 | OTHER |
| CNTNAP2 | 10.1038/nature12213 | OTHER |
| RYR3 | 10.1038/nature12213 | OTHER |
| NRXN1 | 10.1038/nature12213 | OTHER |
| CNTNAP4 | 10.1038/nature12213 | OTHER |
| MUC4 | 10.1038/nature12213 | OTHER |
| PCLO | 10.1038/nature12213 | OTHER |
| LRP2 | 10.1038/nature12213 | OTHER |
| DNAH5 | 10.1038/nature12213 | OTHER |
| CNTN5 | 10.1038/nature12213 | OTHER |
| PARK2 | 10.1038/nature12213 | OTHER |
| BAGE2 | 10.1038/nature12213 | OTHER |
| TPTE | 10.1038/nature12213 | OTHER |
Genelist compiled from: 1. Mutational heterogeneity in cancer and the search for new cancer-associated genes (Lawrence et al. 2013) 2. FLAGS, frequently mutated genes in public exomes (Shyr et al. 2014) - top 20 flags included
Please cite both publications if you find this package useful.
These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.