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survRM2perm: Permutation Test for Comparing Restricted Mean Survival Time

Performs the permutation test using difference in the restricted mean survival time (RMST) between groups as a summary measure of the survival time distribution. When the sample size is less than 50 per group, it has been shown that there is non-negligible inflation of the type I error rate in the commonly used asymptotic test for the RMST comparison. Generally, permutation tests can be useful in such a situation. However, when we apply the permutation test for the RMST comparison, particularly in small sample situations, there are some cases where the survival function in either group cannot be defined due to censoring in the permutation process. Horiguchi and Uno (2020) <doi:10.1002/sim.8565> have examined six workable solutions to handle this numerical issue. It performs permutation tests with implementation of the six methods outlined in the paper when the numerical issue arises during the permutation process. The result of the asymptotic test is also provided for a reference.

Version: 0.1.0
Depends: R (≥ 3.6.0)
Imports: survival, methods, stats4
Published: 2020-06-04
DOI: 10.32614/CRAN.package.survRM2perm
Author: Miki Horiguchi, Hajime Uno
Maintainer: Miki Horiguchi <horiguchimiki at gmail.com>
License: GPL-2
NeedsCompilation: no
Materials: NEWS
CRAN checks: survRM2perm results

Documentation:

Reference manual: survRM2perm.pdf

Downloads:

Package source: survRM2perm_0.1.0.tar.gz
Windows binaries: r-devel: survRM2perm_0.1.0.zip, r-release: survRM2perm_0.1.0.zip, r-oldrel: survRM2perm_0.1.0.zip
macOS binaries: r-release (arm64): survRM2perm_0.1.0.tgz, r-oldrel (arm64): survRM2perm_0.1.0.tgz, r-release (x86_64): survRM2perm_0.1.0.tgz, r-oldrel (x86_64): survRM2perm_0.1.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.