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tLagInterim: Interim Monitoring of Clinical Trials with Time-Lagged Outcome

Implements inverse and augmented inverse probability weighted estimators for common treatment effect parameters at an interim analysis with time-lagged outcome that may not be available for all enrolled subjects. Produces estimators, standard errors, and information that can be used to compute stopping boundaries using software that assumes that the estimators/test statistics have independent increments. Tsiatis, A. A. and Davidian, M., (2022) <doi:10.48550/arXiv.2204.10739> .

Version: 1.0
Depends: R (≥ 3.5.0), survival
Imports: R.utils
Published: 2022-08-17
DOI: 10.32614/CRAN.package.tLagInterim
Author: Shannon T. Holloway [aut, cre], Marie Davidian [aut], Anastasios Tsiatis [aut]
Maintainer: Shannon T. Holloway <shannon.t.holloway at gmail.com>
License: GPL-2
NeedsCompilation: no
CRAN checks: tLagInterim results

Documentation:

Reference manual: tLagInterim.pdf

Downloads:

Package source: tLagInterim_1.0.tar.gz
Windows binaries: r-devel: tLagInterim_1.0.zip, r-release: tLagInterim_1.0.zip, r-oldrel: tLagInterim_1.0.zip
macOS binaries: r-release (arm64): tLagInterim_1.0.tgz, r-oldrel (arm64): tLagInterim_1.0.tgz, r-release (x86_64): tLagInterim_1.0.tgz, r-oldrel (x86_64): tLagInterim_1.0.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.