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Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.
Version: | 0.1.0 |
Imports: | Iso |
Published: | 2018-09-28 |
DOI: | 10.32614/CRAN.package.titeIR |
Author: | Lee McDaniel [aut, cre] |
Maintainer: | Lee McDaniel <lmcda4 at lsuhsc.edu> |
License: | GPL-3 |
NeedsCompilation: | no |
CRAN checks: | titeIR results |
Reference manual: | titeIR.pdf |
Package source: | titeIR_0.1.0.tar.gz |
Windows binaries: | r-devel: titeIR_0.1.0.zip, r-release: titeIR_0.1.0.zip, r-oldrel: titeIR_0.1.0.zip |
macOS binaries: | r-release (arm64): titeIR_0.1.0.tgz, r-oldrel (arm64): titeIR_0.1.0.tgz, r-release (x86_64): titeIR_0.1.0.tgz, r-oldrel (x86_64): titeIR_0.1.0.tgz |
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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.