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volcano-plot

Interactive adverse event (AE) volcano plot for monitoring clinical trial safety. This tool allows users to view the overall distribution of AEs in a clinical trial using standard (e.g. MedDRA preferred term) or custom (e.g. Gender) categories using a volcano plot similar to proposal by Zink et al. (2013). This tool provides a stand-along shiny application and flexible shiny modules allowing this tool to be used as a part of more robust safety monitoring framework like the Shiny app from the ‘safetyGraphics’ R package. License: MIT + file LICENSE

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Sample Code

Install the package from github with devtools::install_github('safetyGraphics/volcanoPlot', ref="main") then run stand-alone app:

library(volcanoPlot)
volcanoApp()

Or run in safetyGraphics:

library(volcanoPlot)

# Load standard graphics from safetyCharts + Volcano plot
charts<-c(
    safetyGraphics::makeChartConfig(),
    safetyGraphics::makeChartConfig(packages="volcanoPlot")
)

# Add default treatment columns
mapping <- list(dm=list('treatment_values--group1'="Placebo", 'treatment_values--group2'="Xanomeline High Dose"))

#Initialize SafetyGraphics app. 
safetyGraphics::safetyGraphicsApp(charts=charts, mapping=mapping)

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.