The hardware and bandwidth for this mirror is donated by METANET, the Webhosting and Full Service-Cloud Provider.
If you wish to report a bug, or if you are interested in having us mirror your free-software or open-source project, please feel free to contact us at mirror[@]metanet.ch.

tsdf: Two-/Three-Stage Designs for Phase 1&2 Clinical Trials

Calculates Zhong's optimal two-/three-stage Phase II designs for single-arm trials, generates target-toxicity decision tables for two-/three-stage Phase I dose-finding, and supports dose-finding simulations using custom decision tables. The Phase II design is based on Zhong (2012) <doi:10.1016/j.cct.2012.07.006>.

Version: 1.1-9
Suggests: knitr, rmarkdown
Published: 2026-04-26
DOI: 10.32614/CRAN.package.tsdf
Author: Wenchuan Guo [aut, cre], Jianan Hui [aut], Bob Zhong [aut]
Maintainer: Wenchuan Guo <wguo1017 at gmail.com>
License: GPL-2
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: tsdf results

Documentation:

Reference manual: tsdf.html , tsdf.pdf
Vignettes: Quick Start Guide (source, R code)

Downloads:

Package source: tsdf_1.1-9.tar.gz
Windows binaries: r-devel: tsdf_1.1-9.zip, r-release: tsdf_1.1-9.zip, r-oldrel: tsdf_1.1-8.zip
macOS binaries: r-release (arm64): tsdf_1.1-9.tgz, r-oldrel (arm64): tsdf_1.1-9.tgz, r-release (x86_64): tsdf_1.1-8.tgz, r-oldrel (x86_64): tsdf_1.1-8.tgz
Old sources: tsdf archive

Linking:

Please use the canonical form https://CRAN.R-project.org/package=tsdf to link to this page.

These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.