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ALLSPICER: ALLelic Spectrum of Pleiotropy Informed Correlated Effects

Provides statistical tools to analyze heterogeneous effects of rare variants within genes that are associated with multiple traits. The package implements methods for assessing pleiotropic effects and identifying allelic heterogeneity, which can be useful in large-scale genetic studies. Methods include likelihood-based statistical tests to assess these effects. For more details, see Lu et al. (2024) <doi:10.1101/2024.10.01.614806>.

Version: 0.1.9
Imports: dplyr, magrittr, readr, mvtnorm, stats
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2024-10-16
DOI: 10.32614/CRAN.package.ALLSPICER
Author: Wenhan Lu [aut, cre]
Maintainer: Wenhan Lu <wlu at broadinstitute.org>
License: MIT + file LICENSE
NeedsCompilation: no
Materials: README
CRAN checks: ALLSPICER results

Documentation:

Reference manual: ALLSPICER.pdf

Downloads:

Package source: ALLSPICER_0.1.9.tar.gz
Windows binaries: r-devel: ALLSPICER_0.1.9.zip, r-release: ALLSPICER_0.1.9.zip, r-oldrel: ALLSPICER_0.1.9.zip
macOS binaries: r-release (arm64): ALLSPICER_0.1.9.tgz, r-oldrel (arm64): ALLSPICER_0.1.9.tgz, r-release (x86_64): ALLSPICER_0.1.9.tgz, r-oldrel (x86_64): ALLSPICER_0.1.9.tgz

Linking:

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These binaries (installable software) and packages are in development.
They may not be fully stable and should be used with caution. We make no claims about them.